Transverse Myelitis in Systemic Sclerosis

Amir M. Torabi, Rahul K. Patel, Gil I. Wolfe, Charlece S. Hughes, Dianne B. Mendelsohn, Jaya R. Trivedi

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Background: Neurological involvement occurs rarely with systemic sclerosis (SSc). Only a few cases of transverse myelopathy have been reported in the setting of SSc. Objective: To describe a patient with SSc who developed transverse myelitis that improved during a course of immunosuppression. Results: A 30-year-old woman with SSc presented with subacute onset of bilateral lower extremity weakness and numbness. Results of magnetic resonance imaging and cerebrospinal fluid studies supported a diagnosis of transverse myelitis. The patient responded favorably to a course of corticosteroids and cyclophosphamide. No overlapping autoimmune disorders were evident. Clinical follow-up showed significant recovery, with resolution of radiological abnormalities. Conclusion: Transverse myelitis can occur as a rare manifestation of SSc and may respond favorably to immunosuppressive therapy.

Original languageEnglish (US)
Pages (from-to)126-128
Number of pages3
JournalArchives of Neurology
Volume61
Issue number1
DOIs
StatePublished - Jan 2004

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Transverse Myelitis
Systemic Scleroderma
Hypesthesia
Spinal Cord Diseases
Immunosuppressive Agents
Cyclophosphamide
Immunosuppression
Cerebrospinal Fluid
Lower Extremity
Adrenal Cortex Hormones
Magnetic Resonance Imaging
Transverse

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Transverse Myelitis in Systemic Sclerosis. / Torabi, Amir M.; Patel, Rahul K.; Wolfe, Gil I.; Hughes, Charlece S.; Mendelsohn, Dianne B.; Trivedi, Jaya R.

In: Archives of Neurology, Vol. 61, No. 1, 01.2004, p. 126-128.

Research output: Contribution to journalArticle

Torabi, Amir M. ; Patel, Rahul K. ; Wolfe, Gil I. ; Hughes, Charlece S. ; Mendelsohn, Dianne B. ; Trivedi, Jaya R. / Transverse Myelitis in Systemic Sclerosis. In: Archives of Neurology. 2004 ; Vol. 61, No. 1. pp. 126-128.
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