Trisomy 2, trisomy 20, and del(17p) as sole chromosomal abnormalities in three cases of hepatoblastoma

V. S. Tonk, K. S. Wilson, C. F. Timmons, N. R. Schneider

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36 Scopus citations


Short‐term cultures of three hepatoblastomas were analyzed cytogenetically. Trisomy 2, trisomy 20, and a deletion of 17p were found as the sole abnormalities, yielding the karyotypes 47,XY, + 2; 47,XX, + 20; and 46,XX,del(17)(p12)/46,XX. This is the first reported case of deletion of 17p as the sole chromosomal abnormality in a hepatoblastoma and the first reported case of trisomy 20 without double minute chromosomes as a sole chromosomal abnormality in hepatoblastoma.

Original languageEnglish (US)
Pages (from-to)199-202
Number of pages4
JournalGenes, Chromosomes and Cancer
Issue number3
StatePublished - Nov 1994


ASJC Scopus subject areas

  • Genetics
  • Cancer Research

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