Trisomy 2, trisomy 20, and del(17p) as sole chromosomal abnormalities in three cases of hepatoblastoma

V. S. Tonk, K. S. Wilson, C. F. Timmons, N. R. Schneider

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Abstract

Short-term cultures of three hepatoblastomas were analyzed cytogenetically. Trisomy 2, trisomy 20, and a deletion of 17p were found as the sole abnormalities, yielding the karyotypes 47,XY, +2; 47,XX, +20; and 46,XX,del(17)(p12)/46,XX. This is the first reported case of deletion of 17p as the sole chromosomal abnormality in a hepatoblastoma and the first reported case of trisomy 20 without double minute chromosomes as a sole chromosomal abnormality in hepatoblastoma.

Original languageEnglish (US)
Pages (from-to)199-202
Number of pages4
JournalGenes Chromosomes and Cancer
Volume11
Issue number3
DOIs
StatePublished - 1994

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Hepatoblastoma
Trisomy
Chromosome Aberrations
Karyotype
Chromosomes
Trisomy Chromosome 20

ASJC Scopus subject areas

  • Cancer Research
  • Genetics

Cite this

Trisomy 2, trisomy 20, and del(17p) as sole chromosomal abnormalities in three cases of hepatoblastoma. / Tonk, V. S.; Wilson, K. S.; Timmons, C. F.; Schneider, N. R.

In: Genes Chromosomes and Cancer, Vol. 11, No. 3, 1994, p. 199-202.

Research output: Contribution to journalArticle

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