@article{9df4a249b9ab4367a9776b9a50e32fe3,
title = "Tumor detection in the bladder wall with a measurement of abnormal thickness in CT scans",
abstract = "Virtual cystoscopy is a developing technique for bladder cancer screening. In a conventional cystoscopy, an optical probe is inserted into the bladder and an expert reviews the appearance of the bladder wall. Physical limitations of the probe place restrictions on the examination of the bladder wall. In virtual cystoscopy, a computed tomography (CT) scan of the bladder is acquired and an expert reviews the appearance of the bladder wall as shown by the CT. The task of identifying tumors in the bladder wall has often been done without extensive computational aid to the expert. We have developed an image processing algorithm that aids the expert in the detection of bladder tumors. Compared with an expert observer reading the CT, our algorithm achieves 89% sensitivity, 88% specificity, 48% positive predictive value, and 98% negative predictive value.",
keywords = "Anatomical atlas, Bladder wall, Computer-aided diagnosis, Thickness measurement, Tumor detection, Virtual cystoscopy, Virtual endoscopy",
author = "Sylvain Jaume and Matthieu Ferrant and Beno{\^i}t Macq and Lennox Hoyte and Fielding, {Julia R.} and Andreas Schreyer and Ron Kikinis and Warfield, {Simon K.}",
note = "Funding Information: Manuscript received December 4, 2001; revised November 1, 2002. This work was supported in part by the Belgian Science Foundation (FRIA and FNRS) and in part by the National Cancer Institute under Grant NIH P41 RR13218, Grant NIH P01 CA67165, Grant NIH R01 RR11747, Grant R01EB000304, and Grant R21-CA80945-01. Asterisk indicates corresponding author. S. Jaume is with the Telecommunications Laboratory, Universit{\'e} Catholique de Louvain, 1348 Louvain-la-Neuve, Belgium (e-mail: jaume@tele.ucl.ac.be). M. Ferrant is with General Electric Medical Systems Europe, 78530 Buc, France. B. Macq is with the Telecommunications Laboratory, Universit{\'e} Catholique de Louvain, 1348 Louvain-la-Neuve, Belgium. L. Hoyte, A. Schreyer, R. Kikinis, and S. K. Warfield are with the Brigham and Women{\textquoteright}s Hospital, Harvard Medical School, Boston, MA 02115 USA. J. R. Fielding is with the University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 USA. Digital Object Identifier 10.1109/TBME.2003.808828 Fig. 1. CT scan of the abdomen shows the bladder cavity in black, and the bladder wall in light gray (thin contour around the cavity). (left) Slice through an abdomen CT scan for one patient. (right) Slice through an abdomen CT scan for a second patient. The arrows point to wall regions with abnormal thickness.",
year = "2003",
month = mar,
day = "1",
doi = "10.1109/TBME.2003.808828",
language = "English (US)",
volume = "50",
pages = "383--390",
journal = "IEEE Transactions on Biomedical Engineering",
issn = "0018-9294",
publisher = "IEEE Computer Society",
number = "3",
}