Ultrasound as an outcome measure to assess disease activity in disorders of skin thickening: An example of the use of radiologic techniques to assess skin disease

Sandra E. Bendeck, Heidi T. Jacobe

Research output: Contribution to journalReview article

37 Scopus citations

Abstract

Good outcome measures are required to determine whether a therapy is effective, both in routine clinical practice and in experimental clinical trials. In disorders of skin thickening such as morphea and scleroderma, more commonly used outcome measures that use a subjective score based on palpated skin thickening are fraught with error. By contrast, measurements made by ultrasound have great promise as outcome measures that are quantitative, valid, reproducible, and responsive. Further studies should establish its role in the field. In this paper, the present authors used ultrasound to illustrate the criteria that are required to establish a technology-based outcome measure.

Original languageEnglish (US)
Pages (from-to)86-92
Number of pages7
JournalDermatologic Therapy
Volume20
Issue number2
DOIs
StatePublished - Mar 2007

Keywords

  • Morphea
  • Outcome measure
  • Scleroderma
  • Ultrasound

ASJC Scopus subject areas

  • Dermatology

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