Unexpected Hepatitis B virus infection after liver transplantation - United States, 2014-2019

Danae Bixler; Pallavi Annambhotla; Martha P. Montgomery; Tonya Mixon-Hayden; Ben Kupronis; Marian G. Michaels; Ricardo M. la Hoz; Sridhar V. Basavaraju; Saleem Kamili; Anne Moorman

doi:10.15585/MMWR.MM7027A1

Unexpected Hepatitis B virus infection after liver transplantation - United States, 2014-2019

Danae Bixler, Pallavi Annambhotla, Martha P. Montgomery, Tonya Mixon-Hayden, Ben Kupronis, Marian G. Michaels, Ricardo M. la Hoz, Sridhar V. Basavaraju, Saleem Kamili, Anne Moorman

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Abstract

What is already known about this topic? Unexpected donor-derived hepatitis B virus (HBV) infection after organ transplantation is rare and is associated most commonly with donor injection drug use. What is added by this report? During 2019, the Organ Procurement and Transplantation Network and CDC received an increased number of reports of HBV infection among liver recipients from HBV-negative donors; 12 of 14 implicated donors had evidence of recent injection drug use, and 13 donors were hepatitis C virus (HCV)-seropositive. What are the implications for public health practice? Providers caring for recipients of organs from donors who are HCV-seropositive or who recently injected drugs should maintain awareness of infectious complications of drug use and monitor recipients accordingly.

Original language	English (US)
Pages (from-to)	961-966
Number of pages	6
Journal	Morbidity and Mortality Weekly Report
Volume	70
Issue number	27
DOIs	https://doi.org/10.15585/MMWR.MM7027A1
State	Published - Jul 2021

ASJC Scopus subject areas

Epidemiology
Health(social science)
Health, Toxicology and Mutagenesis
Health Information Management

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10.15585/MMWR.MM7027A1

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title = "Unexpected Hepatitis B virus infection after liver transplantation - United States, 2014-2019",

abstract = "What is already known about this topic? Unexpected donor-derived hepatitis B virus (HBV) infection after organ transplantation is rare and is associated most commonly with donor injection drug use. What is added by this report? During 2019, the Organ Procurement and Transplantation Network and CDC received an increased number of reports of HBV infection among liver recipients from HBV-negative donors; 12 of 14 implicated donors had evidence of recent injection drug use, and 13 donors were hepatitis C virus (HCV)-seropositive. What are the implications for public health practice? Providers caring for recipients of organs from donors who are HCV-seropositive or who recently injected drugs should maintain awareness of infectious complications of drug use and monitor recipients accordingly.",

author = "Danae Bixler and Pallavi Annambhotla and Montgomery, {Martha P.} and Tonya Mixon-Hayden and Ben Kupronis and Michaels, {Marian G.} and {la Hoz}, {Ricardo M.} and Basavaraju, {Sridhar V.} and Saleem Kamili and Anne Moorman",

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month = jul,

doi = "10.15585/MMWR.MM7027A1",

language = "English (US)",

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pages = "961--966",

journal = "Morbidity and Mortality Weekly Report",

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T1 - Unexpected Hepatitis B virus infection after liver transplantation - United States, 2014-2019

AU - Bixler, Danae

AU - Annambhotla, Pallavi

AU - Montgomery, Martha P.

AU - Mixon-Hayden, Tonya

AU - Kupronis, Ben

AU - Michaels, Marian G.

AU - la Hoz, Ricardo M.

AU - Basavaraju, Sridhar V.

AU - Kamili, Saleem

AU - Moorman, Anne

PY - 2021/7

Y1 - 2021/7

N2 - What is already known about this topic? Unexpected donor-derived hepatitis B virus (HBV) infection after organ transplantation is rare and is associated most commonly with donor injection drug use. What is added by this report? During 2019, the Organ Procurement and Transplantation Network and CDC received an increased number of reports of HBV infection among liver recipients from HBV-negative donors; 12 of 14 implicated donors had evidence of recent injection drug use, and 13 donors were hepatitis C virus (HCV)-seropositive. What are the implications for public health practice? Providers caring for recipients of organs from donors who are HCV-seropositive or who recently injected drugs should maintain awareness of infectious complications of drug use and monitor recipients accordingly.

AB - What is already known about this topic? Unexpected donor-derived hepatitis B virus (HBV) infection after organ transplantation is rare and is associated most commonly with donor injection drug use. What is added by this report? During 2019, the Organ Procurement and Transplantation Network and CDC received an increased number of reports of HBV infection among liver recipients from HBV-negative donors; 12 of 14 implicated donors had evidence of recent injection drug use, and 13 donors were hepatitis C virus (HCV)-seropositive. What are the implications for public health practice? Providers caring for recipients of organs from donors who are HCV-seropositive or who recently injected drugs should maintain awareness of infectious complications of drug use and monitor recipients accordingly.

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Unexpected Hepatitis B virus infection after liver transplantation - United States, 2014-2019

Abstract

ASJC Scopus subject areas

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