Unmasking MASC: Bringing to Light the Unique Morphologic, Immunohistochemical and Genetic Features of the Newly Recognized Mammary Analogue Secretory Carcinoma of Salivary Glands

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Abstract

Mammary analogue secretory carcinoma (MASC) is a recently described salivary gland neoplasm that is characterized by its striking morphologic and molecular similarities to secretory carcinoma of the breast. This review highlights the characteristic clinical, histologic, immunophenotypic, and molecular features of MASC, and draws attention to the differential diagnosis of this increasingly recognized tumor.

Original languageEnglish (US)
Pages (from-to)35-39
Number of pages5
JournalHead and Neck Pathology
Volume7
Issue number1
DOIs
StatePublished - Mar 5 2013

Keywords

  • Acinic cell carcinoma
  • ETV6-NTRK3
  • Mammaglobin
  • Mammary analogue secretory carcinoma
  • Secretory carcinoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Otorhinolaryngology
  • Oncology

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