Unmasking MASC: Bringing to Light the Unique Morphologic, Immunohistochemical and Genetic Features of the Newly Recognized Mammary Analogue Secretory Carcinoma of Salivary Glands

Justin A. Bishop

doi:10.1007/s12105-013-0429-0

Unmasking MASC: Bringing to Light the Unique Morphologic, Immunohistochemical and Genetic Features of the Newly Recognized Mammary Analogue Secretory Carcinoma of Salivary Glands

Justin A. Bishop

Research output: Contribution to journal › Article › peer-review

104 Scopus citations

Abstract

Mammary analogue secretory carcinoma (MASC) is a recently described salivary gland neoplasm that is characterized by its striking morphologic and molecular similarities to secretory carcinoma of the breast. This review highlights the characteristic clinical, histologic, immunophenotypic, and molecular features of MASC, and draws attention to the differential diagnosis of this increasingly recognized tumor.

Original language	English (US)
Pages (from-to)	35-39
Number of pages	5
Journal	Head and Neck Pathology
Volume	7
Issue number	1
DOIs	https://doi.org/10.1007/s12105-013-0429-0
State	Published - Mar 2013

Keywords

Acinic cell carcinoma
ETV6-NTRK3
Mammaglobin
Mammary analogue secretory carcinoma
Secretory carcinoma

ASJC Scopus subject areas

Pathology and Forensic Medicine
Otorhinolaryngology
Oncology

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10.1007/s12105-013-0429-0

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abstract = "Mammary analogue secretory carcinoma (MASC) is a recently described salivary gland neoplasm that is characterized by its striking morphologic and molecular similarities to secretory carcinoma of the breast. This review highlights the characteristic clinical, histologic, immunophenotypic, and molecular features of MASC, and draws attention to the differential diagnosis of this increasingly recognized tumor.",

keywords = "Acinic cell carcinoma, ETV6-NTRK3, Mammaglobin, Mammary analogue secretory carcinoma, Secretory carcinoma",

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AB - Mammary analogue secretory carcinoma (MASC) is a recently described salivary gland neoplasm that is characterized by its striking morphologic and molecular similarities to secretory carcinoma of the breast. This review highlights the characteristic clinical, histologic, immunophenotypic, and molecular features of MASC, and draws attention to the differential diagnosis of this increasingly recognized tumor.

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KW - Mammaglobin

KW - Mammary analogue secretory carcinoma

KW - Secretory carcinoma

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Unmasking MASC: Bringing to Light the Unique Morphologic, Immunohistochemical and Genetic Features of the Newly Recognized Mammary Analogue Secretory Carcinoma of Salivary Glands

Abstract

Keywords

ASJC Scopus subject areas

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