Unraveling the mechanisms of obesity-induced hyperoxaluria

Research output: Contribution to journalComment/debate

3 Scopus citations

Abstract

Kidney stones is increasingly associated with obesity. With an increasing prevalence of obesity and metabolic syndrome in the past 30 years, urinary oxalate has significantly increased. However, its underlying pathophysiologic mechanisms of hyperoxaluria have not been fully explored. This preclinical study suggests that hyperoxaluria in obesity depends on a complex network of inflammatory responses linked to metabolic outcome. The future mechanistic and clinical investigations must be targeted at elucidating the pathogenetic role of inflammation in obesity induced hyperoxaluria.

Original languageEnglish (US)
Pages (from-to)1038-1040
Number of pages3
JournalKidney International
Volume93
Issue number5
DOIs
StatePublished - May 1 2018

ASJC Scopus subject areas

  • Nephrology

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