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Use of the nuclear receptor PXR to predict drug interactions
John T. Moore,
Steven A. Kliewer
Molecular Biology
Pharmacology
Molecular Biology
Research output
:
Contribution to journal
›
Article
›
peer-review
177
Scopus citations
Overview
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Medicine & Life Sciences
Pregnane X Receptor
98%
Cytoplasmic and Nuclear Receptors
69%
Drug Interactions
66%
Cytochrome P-450 CYP3A
60%
Mixed Function Oxygenases
59%
Xenobiotics
16%
Gene Expression
13%
Genes
12%
Pregnenolone Carbonitrile
11%
Retinoid X Receptors
10%
Thyroid Hormone Receptors
9%
Retinoids
8%
Response Elements
8%
Rifampin
8%
Drug Development
7%
Intestines
6%
Pharmaceutical Preparations
6%
Steroids
5%
Rabbits
5%
Liver
3%
Chemical Compounds
Pregnane
100%
Cytochrome P450
56%
Drug
35%
Retinoid
19%
Xenobiotic Agent
17%
Pregnenolone
10%
Rifampicin
10%
Thyroid Hormone
10%
Heterodimer
8%
Steroid
6%
Pharmacological Metabolism
5%