Utility of Intravascular Ultrasound in Percutaneous Revascularization of Chronic Total Occlusions: An Overview

Alfredo R. Galassi, Satoru Sumitsuji, Marouane Boukhris, Emmanouil S. Brilakis, Carlo Di Mario, Roberto Garbo, James C. Spratt, Evald H. Christiansen, Andrea Gagnor, Alexandre Avran, Georgios Sianos, Gerald S. Werner

Research output: Contribution to journalReview article

16 Scopus citations


Intravascular ultrasound has been used for >20 years to guide percutaneous coronary intervention in different subsets of coronary lesions. During the last decade, the interest in percutaneous coronary intervention for chronic total occlusion (CTO) has increased dramatically, leading to high success rates. Failure of guidewire crossing is the most common reason for failed CTO attempts. Certain angiographic features, such as blunt proximal CTO cap, tortuosity, heavy calcification, and lack of visibility of path in the distal vessel, increase procedural difficulty. A better understanding of the behavior of the guidewire within the CTO segment may represent a key issue to achieve successful outcome. In this respect, intravascular ultrasound imaging might have potential roles in the recanalization of CTOs. In this paper, we focused on the usefulness and the applications of intravascular ultrasound imaging in percutaneous CTO recanalization, underlying its impact on clinical outcome.

Original languageEnglish (US)
Pages (from-to)1979-1991
Number of pages13
JournalJACC: Cardiovascular Interventions
Issue number19
StatePublished - Oct 10 2016



  • chronic total occlusions
  • intracoronary imaging
  • intravascular ultrasound
  • PCI

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Galassi, A. R., Sumitsuji, S., Boukhris, M., Brilakis, E. S., Di Mario, C., Garbo, R., Spratt, J. C., Christiansen, E. H., Gagnor, A., Avran, A., Sianos, G., & Werner, G. S. (2016). Utility of Intravascular Ultrasound in Percutaneous Revascularization of Chronic Total Occlusions: An Overview. JACC: Cardiovascular Interventions, 9(19), 1979-1991. https://doi.org/10.1016/j.jcin.2016.06.057