Variable effects of heart rate on phasic and regional left ventricular muscle blood flow in anaesthetized dogs

Gerald D. Buckberg, David E Fixler, Joseph P. Archie, R. Peter Henney, Julien I E Hoffman

Research output: Contribution to journalArticle

40 Scopus citations


AUTHORS' SYNOPSIS: Tachycardia to 240 beats/min in anaesthetized dogs increases coronary blood flow while flow in the left ventricular wall remains homogeneous. An arteriovenous fistula causes subendocardial ischaemia at 120 beats/min but pacing to 180 to 210 beats/min increases subendocardial blood flow by increasing diastolic coronary driving pressure per minute.

Original languageEnglish (US)
Pages (from-to)1-11
Number of pages11
JournalCardiovascular Research
Issue number1
Publication statusPublished - Jan 1975


ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Physiology
  • Cardiology and Cardiovascular Medicine

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