Visibility of microcalcifications in CCD-based cone beam CT: A preliminary study

Youtao Shen, Lingyun Chen, Shuaiping Ge, Ying Yi, Tao Han, Yuncheng Zhong, Chao Jen Lai, Xinming Liu, Tianpeng Wang, Chris C. Shaw

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

In this work, we investigated the visibility of microcalcifications in CCD-based cone beam CT (CBCT) breast imaging. A paraffin cylinder with a diameter of 135 mm and a thickness of 40 mm was used to simulate a 100% adipose breast. Calcium carbonate grains, ranging from 140-150 to 200-212 μmu; m in size, were used to simulate the microcalcifications. Groups of 25 same size microcalcifications were arranged into 5 × 5 clusters. Each cluster was embedded at the center of a smaller (15 mm diameter) cylindrical paraffin phantom, which were inserted into a hole at the center of the breast phantom. The breast phantom with the simulated microcalcifications was scanned on a bench top experimental CCDbased cone beam CT system at various exposure levels with two CCD cameras: Hamamatsu's C4742-56-12ER and Dalsa 99-66-0000-00. 300 projection images were acquired over 360 and reconstructed with Feldkamp's backprojection algorithm using a ramp filter. The images were reviewed by 6 readers independently. The ratios of visible microcalcifications were recorded and averaged over all readers. These ratios were plotted as the function of measured image signal-to-noise ratio (SNR) for various scans. It was found that 94% visibility was achieved for 200-212 μmu; m calcifications at an SNR of 48.2 while 50% visibility was achieved for 200-212, 180-200, 160-180, 150-160 and 140-150 μmu; m calcifications at an SNR of 25.0, 35.3, 38.2, 42.2 and 64.4, respectively.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2009
Subtitle of host publicationPhysics of Medical Imaging
Volume7258
DOIs
StatePublished - Jun 15 2009
EventMedical Imaging 2009: Physics of Medical Imaging - Lake Buena Vista, FL, United States
Duration: Feb 9 2009Feb 12 2009

Other

OtherMedical Imaging 2009: Physics of Medical Imaging
CountryUnited States
CityLake Buena Vista, FL
Period2/9/092/12/09

Fingerprint

Calcinosis
Charge coupled devices
visibility
Visibility
breast
Cones
charge coupled devices
Signal to noise ratio
cones
Signal-To-Noise Ratio
Breast
calcification
Paraffin
Paraffins
signal to noise ratios
paraffins
readers
Calcium Carbonate
Calcium carbonate
CCD cameras

Keywords

  • CCD detector
  • Cone beam computed tomography
  • Dose
  • Microcalcification
  • Signal-to-noise ratio

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Shen, Y., Chen, L., Ge, S., Yi, Y., Han, T., Zhong, Y., ... Shaw, C. C. (2009). Visibility of microcalcifications in CCD-based cone beam CT: A preliminary study. In Medical Imaging 2009: Physics of Medical Imaging (Vol. 7258). [72580M] https://doi.org/10.1117/12.813806

Visibility of microcalcifications in CCD-based cone beam CT : A preliminary study. / Shen, Youtao; Chen, Lingyun; Ge, Shuaiping; Yi, Ying; Han, Tao; Zhong, Yuncheng; Lai, Chao Jen; Liu, Xinming; Wang, Tianpeng; Shaw, Chris C.

Medical Imaging 2009: Physics of Medical Imaging. Vol. 7258 2009. 72580M.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Shen, Y, Chen, L, Ge, S, Yi, Y, Han, T, Zhong, Y, Lai, CJ, Liu, X, Wang, T & Shaw, CC 2009, Visibility of microcalcifications in CCD-based cone beam CT: A preliminary study. in Medical Imaging 2009: Physics of Medical Imaging. vol. 7258, 72580M, Medical Imaging 2009: Physics of Medical Imaging, Lake Buena Vista, FL, United States, 2/9/09. https://doi.org/10.1117/12.813806
Shen Y, Chen L, Ge S, Yi Y, Han T, Zhong Y et al. Visibility of microcalcifications in CCD-based cone beam CT: A preliminary study. In Medical Imaging 2009: Physics of Medical Imaging. Vol. 7258. 2009. 72580M https://doi.org/10.1117/12.813806
Shen, Youtao ; Chen, Lingyun ; Ge, Shuaiping ; Yi, Ying ; Han, Tao ; Zhong, Yuncheng ; Lai, Chao Jen ; Liu, Xinming ; Wang, Tianpeng ; Shaw, Chris C. / Visibility of microcalcifications in CCD-based cone beam CT : A preliminary study. Medical Imaging 2009: Physics of Medical Imaging. Vol. 7258 2009.
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abstract = "In this work, we investigated the visibility of microcalcifications in CCD-based cone beam CT (CBCT) breast imaging. A paraffin cylinder with a diameter of 135 mm and a thickness of 40 mm was used to simulate a 100{\%} adipose breast. Calcium carbonate grains, ranging from 140-150 to 200-212 μmu; m in size, were used to simulate the microcalcifications. Groups of 25 same size microcalcifications were arranged into 5 × 5 clusters. Each cluster was embedded at the center of a smaller (15 mm diameter) cylindrical paraffin phantom, which were inserted into a hole at the center of the breast phantom. The breast phantom with the simulated microcalcifications was scanned on a bench top experimental CCDbased cone beam CT system at various exposure levels with two CCD cameras: Hamamatsu's C4742-56-12ER and Dalsa 99-66-0000-00. 300 projection images were acquired over 360 and reconstructed with Feldkamp's backprojection algorithm using a ramp filter. The images were reviewed by 6 readers independently. The ratios of visible microcalcifications were recorded and averaged over all readers. These ratios were plotted as the function of measured image signal-to-noise ratio (SNR) for various scans. It was found that 94{\%} visibility was achieved for 200-212 μmu; m calcifications at an SNR of 48.2 while 50{\%} visibility was achieved for 200-212, 180-200, 160-180, 150-160 and 140-150 μmu; m calcifications at an SNR of 25.0, 35.3, 38.2, 42.2 and 64.4, respectively.",
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