Who Put the “A” in ATP? Generation of ATP from ADP-Ribose in the Nucleus for Hormone-Dependent Gene Regulation

Keun Woo Ryu, W. Lee Kraus

Research output: Contribution to journalShort survey


In a recent issue of Science, Wright et al. (2016) describe a pathway for the synthesis of nuclear ATP, leading from NAD+ to poly(ADP-ribose) to ADP-ribose to ATP, which supports the activity of ATP-dependent chromatin remodeling enzymes during hormone-dependent transcription.

Original languageEnglish (US)
Pages (from-to)349-351
Number of pages3
JournalMolecular Cell
Issue number3
StatePublished - Aug 4 2016


ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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