Whole-heart coronary MR angiography using image-based navigation for the detection of coronary anomalies in adult patients with congenital heart disease

Markus Henningsson, Tarique Hussain, Miguel S. Vieira, Gerald F. Greil, Jouke Smink, Gerald V. Ensbergen, Gabrielle Beck, Rene M. Botnar

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Background The purpose of this study was to evaluate a recently developed two-dimensional (2D) image-based navigation approach (iNAVG+C) combined with respiratory bellows gating for CMRA in patients with congenital heart disease. Methods Nine healthy volunteers (mean age 32 ± 6 years [standard deviation]) and 29 patients (28 ± 9 years) were scanned on a 1.5 Tesla clinical scanner using iNAVG+C motion compensated T2prepared CMRA, and the conventional 1D NAV approach. Scan time was recorded for each CMRA scan. An image quality score was given to each coronary artery from (0, uninterpretable; to 4, excellent image quality). Additionally, vessel sharpness of each coronary artery was measured. Results Average scan time was significantly shorter (P < 0.01) using the proposed iNAVC+G approach (7:57 ± 1:34) compared with 1D NAV (9:15 ± 3:02). Improved visual scores of the right coronary artery (iNAVG+C: 4,3,4 (median, 25th percentile, 75th percentile) versus 1D NAV: 3,3,4; P < 0.001) and left anterior descending artery (iNAVG+C: 3,3,4 versus 1D NAV: 3,2,3; P < 0.001) were obtained using iNAVG+C compared with 1D NAV as well as an increased vessel sharpness of the right coronary artery (iNAVG+C: 65.3% ± 6.6% (mean ± standard deviation) versus 1D NAV: 60.2% ± 11.4%; P < 0.05) and left anterior descending artery (iNAVG+C: 63.2% ± 6.7% versus 1D NAV: 58.3% ± 9.5%; P < 0.05). Conclusion Image-based navigation in combination with respiratory bellows gating allows for more robust suppression of respiratory motion artifacts for whole-heart CMRA compared with conventional 1D NAV as images can be acquired in a shorter time and with improved image quality.

Original languageEnglish (US)
Pages (from-to)947-955
Number of pages9
JournalJournal of Magnetic Resonance Imaging
Volume43
Issue number4
DOIs
StatePublished - Apr 1 2016

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Coronary Angiography
Heart Diseases
Coronary Vessels
Arteries
Artifacts
Healthy Volunteers

Keywords

  • congenital heart disease
  • coronary magnetic resonance angiography
  • image-based respiratory navigation
  • respiratory motion correction

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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Whole-heart coronary MR angiography using image-based navigation for the detection of coronary anomalies in adult patients with congenital heart disease. / Henningsson, Markus; Hussain, Tarique; Vieira, Miguel S.; Greil, Gerald F.; Smink, Jouke; Ensbergen, Gerald V.; Beck, Gabrielle; Botnar, Rene M.

In: Journal of Magnetic Resonance Imaging, Vol. 43, No. 4, 01.04.2016, p. 947-955.

Research output: Contribution to journalArticle

Henningsson, Markus ; Hussain, Tarique ; Vieira, Miguel S. ; Greil, Gerald F. ; Smink, Jouke ; Ensbergen, Gerald V. ; Beck, Gabrielle ; Botnar, Rene M. / Whole-heart coronary MR angiography using image-based navigation for the detection of coronary anomalies in adult patients with congenital heart disease. In: Journal of Magnetic Resonance Imaging. 2016 ; Vol. 43, No. 4. pp. 947-955.
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abstract = "Background The purpose of this study was to evaluate a recently developed two-dimensional (2D) image-based navigation approach (iNAVG+C) combined with respiratory bellows gating for CMRA in patients with congenital heart disease. Methods Nine healthy volunteers (mean age 32 ± 6 years [standard deviation]) and 29 patients (28 ± 9 years) were scanned on a 1.5 Tesla clinical scanner using iNAVG+C motion compensated T2prepared CMRA, and the conventional 1D NAV approach. Scan time was recorded for each CMRA scan. An image quality score was given to each coronary artery from (0, uninterpretable; to 4, excellent image quality). Additionally, vessel sharpness of each coronary artery was measured. Results Average scan time was significantly shorter (P < 0.01) using the proposed iNAVC+G approach (7:57 ± 1:34) compared with 1D NAV (9:15 ± 3:02). Improved visual scores of the right coronary artery (iNAVG+C: 4,3,4 (median, 25th percentile, 75th percentile) versus 1D NAV: 3,3,4; P < 0.001) and left anterior descending artery (iNAVG+C: 3,3,4 versus 1D NAV: 3,2,3; P < 0.001) were obtained using iNAVG+C compared with 1D NAV as well as an increased vessel sharpness of the right coronary artery (iNAVG+C: 65.3{\%} ± 6.6{\%} (mean ± standard deviation) versus 1D NAV: 60.2{\%} ± 11.4{\%}; P < 0.05) and left anterior descending artery (iNAVG+C: 63.2{\%} ± 6.7{\%} versus 1D NAV: 58.3{\%} ± 9.5{\%}; P < 0.05). Conclusion Image-based navigation in combination with respiratory bellows gating allows for more robust suppression of respiratory motion artifacts for whole-heart CMRA compared with conventional 1D NAV as images can be acquired in a shorter time and with improved image quality.",
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AU - Henningsson, Markus

AU - Hussain, Tarique

AU - Vieira, Miguel S.

AU - Greil, Gerald F.

AU - Smink, Jouke

AU - Ensbergen, Gerald V.

AU - Beck, Gabrielle

AU - Botnar, Rene M.

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N2 - Background The purpose of this study was to evaluate a recently developed two-dimensional (2D) image-based navigation approach (iNAVG+C) combined with respiratory bellows gating for CMRA in patients with congenital heart disease. Methods Nine healthy volunteers (mean age 32 ± 6 years [standard deviation]) and 29 patients (28 ± 9 years) were scanned on a 1.5 Tesla clinical scanner using iNAVG+C motion compensated T2prepared CMRA, and the conventional 1D NAV approach. Scan time was recorded for each CMRA scan. An image quality score was given to each coronary artery from (0, uninterpretable; to 4, excellent image quality). Additionally, vessel sharpness of each coronary artery was measured. Results Average scan time was significantly shorter (P < 0.01) using the proposed iNAVC+G approach (7:57 ± 1:34) compared with 1D NAV (9:15 ± 3:02). Improved visual scores of the right coronary artery (iNAVG+C: 4,3,4 (median, 25th percentile, 75th percentile) versus 1D NAV: 3,3,4; P < 0.001) and left anterior descending artery (iNAVG+C: 3,3,4 versus 1D NAV: 3,2,3; P < 0.001) were obtained using iNAVG+C compared with 1D NAV as well as an increased vessel sharpness of the right coronary artery (iNAVG+C: 65.3% ± 6.6% (mean ± standard deviation) versus 1D NAV: 60.2% ± 11.4%; P < 0.05) and left anterior descending artery (iNAVG+C: 63.2% ± 6.7% versus 1D NAV: 58.3% ± 9.5%; P < 0.05). Conclusion Image-based navigation in combination with respiratory bellows gating allows for more robust suppression of respiratory motion artifacts for whole-heart CMRA compared with conventional 1D NAV as images can be acquired in a shorter time and with improved image quality.

AB - Background The purpose of this study was to evaluate a recently developed two-dimensional (2D) image-based navigation approach (iNAVG+C) combined with respiratory bellows gating for CMRA in patients with congenital heart disease. Methods Nine healthy volunteers (mean age 32 ± 6 years [standard deviation]) and 29 patients (28 ± 9 years) were scanned on a 1.5 Tesla clinical scanner using iNAVG+C motion compensated T2prepared CMRA, and the conventional 1D NAV approach. Scan time was recorded for each CMRA scan. An image quality score was given to each coronary artery from (0, uninterpretable; to 4, excellent image quality). Additionally, vessel sharpness of each coronary artery was measured. Results Average scan time was significantly shorter (P < 0.01) using the proposed iNAVC+G approach (7:57 ± 1:34) compared with 1D NAV (9:15 ± 3:02). Improved visual scores of the right coronary artery (iNAVG+C: 4,3,4 (median, 25th percentile, 75th percentile) versus 1D NAV: 3,3,4; P < 0.001) and left anterior descending artery (iNAVG+C: 3,3,4 versus 1D NAV: 3,2,3; P < 0.001) were obtained using iNAVG+C compared with 1D NAV as well as an increased vessel sharpness of the right coronary artery (iNAVG+C: 65.3% ± 6.6% (mean ± standard deviation) versus 1D NAV: 60.2% ± 11.4%; P < 0.05) and left anterior descending artery (iNAVG+C: 63.2% ± 6.7% versus 1D NAV: 58.3% ± 9.5%; P < 0.05). Conclusion Image-based navigation in combination with respiratory bellows gating allows for more robust suppression of respiratory motion artifacts for whole-heart CMRA compared with conventional 1D NAV as images can be acquired in a shorter time and with improved image quality.

KW - congenital heart disease

KW - coronary magnetic resonance angiography

KW - image-based respiratory navigation

KW - respiratory motion correction

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