TY - JOUR
T1 - Whole-heart coronary MR angiography using image-based navigation for the detection of coronary anomalies in adult patients with congenital heart disease
AU - Henningsson, Markus
AU - Hussain, Tarique
AU - Vieira, Miguel S.
AU - Greil, Gerald F.
AU - Smink, Jouke
AU - Ensbergen, Gerald V.
AU - Beck, Gabrielle
AU - Botnar, Rene M.
N1 - Publisher Copyright:
© 2015 Wiley Periodicals, Inc.
PY - 2016/4/1
Y1 - 2016/4/1
N2 - Background The purpose of this study was to evaluate a recently developed two-dimensional (2D) image-based navigation approach (iNAVG+C) combined with respiratory bellows gating for CMRA in patients with congenital heart disease. Methods Nine healthy volunteers (mean age 32 ± 6 years [standard deviation]) and 29 patients (28 ± 9 years) were scanned on a 1.5 Tesla clinical scanner using iNAVG+C motion compensated T2prepared CMRA, and the conventional 1D NAV approach. Scan time was recorded for each CMRA scan. An image quality score was given to each coronary artery from (0, uninterpretable; to 4, excellent image quality). Additionally, vessel sharpness of each coronary artery was measured. Results Average scan time was significantly shorter (P < 0.01) using the proposed iNAVC+G approach (7:57 ± 1:34) compared with 1D NAV (9:15 ± 3:02). Improved visual scores of the right coronary artery (iNAVG+C: 4,3,4 (median, 25th percentile, 75th percentile) versus 1D NAV: 3,3,4; P < 0.001) and left anterior descending artery (iNAVG+C: 3,3,4 versus 1D NAV: 3,2,3; P < 0.001) were obtained using iNAVG+C compared with 1D NAV as well as an increased vessel sharpness of the right coronary artery (iNAVG+C: 65.3% ± 6.6% (mean ± standard deviation) versus 1D NAV: 60.2% ± 11.4%; P < 0.05) and left anterior descending artery (iNAVG+C: 63.2% ± 6.7% versus 1D NAV: 58.3% ± 9.5%; P < 0.05). Conclusion Image-based navigation in combination with respiratory bellows gating allows for more robust suppression of respiratory motion artifacts for whole-heart CMRA compared with conventional 1D NAV as images can be acquired in a shorter time and with improved image quality.
AB - Background The purpose of this study was to evaluate a recently developed two-dimensional (2D) image-based navigation approach (iNAVG+C) combined with respiratory bellows gating for CMRA in patients with congenital heart disease. Methods Nine healthy volunteers (mean age 32 ± 6 years [standard deviation]) and 29 patients (28 ± 9 years) were scanned on a 1.5 Tesla clinical scanner using iNAVG+C motion compensated T2prepared CMRA, and the conventional 1D NAV approach. Scan time was recorded for each CMRA scan. An image quality score was given to each coronary artery from (0, uninterpretable; to 4, excellent image quality). Additionally, vessel sharpness of each coronary artery was measured. Results Average scan time was significantly shorter (P < 0.01) using the proposed iNAVC+G approach (7:57 ± 1:34) compared with 1D NAV (9:15 ± 3:02). Improved visual scores of the right coronary artery (iNAVG+C: 4,3,4 (median, 25th percentile, 75th percentile) versus 1D NAV: 3,3,4; P < 0.001) and left anterior descending artery (iNAVG+C: 3,3,4 versus 1D NAV: 3,2,3; P < 0.001) were obtained using iNAVG+C compared with 1D NAV as well as an increased vessel sharpness of the right coronary artery (iNAVG+C: 65.3% ± 6.6% (mean ± standard deviation) versus 1D NAV: 60.2% ± 11.4%; P < 0.05) and left anterior descending artery (iNAVG+C: 63.2% ± 6.7% versus 1D NAV: 58.3% ± 9.5%; P < 0.05). Conclusion Image-based navigation in combination with respiratory bellows gating allows for more robust suppression of respiratory motion artifacts for whole-heart CMRA compared with conventional 1D NAV as images can be acquired in a shorter time and with improved image quality.
KW - congenital heart disease
KW - coronary magnetic resonance angiography
KW - image-based respiratory navigation
KW - respiratory motion correction
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U2 - 10.1002/jmri.25058
DO - 10.1002/jmri.25058
M3 - Article
C2 - 26451972
AN - SCOPUS:84944144917
SN - 1053-1807
VL - 43
SP - 947
EP - 955
JO - Journal of Magnetic Resonance Imaging
JF - Journal of Magnetic Resonance Imaging
IS - 4
ER -