Abstract
Epigenetic regulator plays a pivotal role in breast cancer progression. We recently demonstrated that the epigenetic reader zinc finger MYND-type containing 8 (ZMYND8) mediates breast cancer progression and metastasis by activating hypoxia-inducible factor (HIF). This discovery provides new insights into the molecular mechanism underlying HIF activation and breast cancer progression.
Original language | English (US) |
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Article number | e1479619 |
Journal | Molecular and Cellular Oncology |
Volume | 5 |
Issue number | 4 |
DOIs | |
State | Published - Jul 4 2018 |
Keywords
- Hypoxia-inducible factor
- breast cancer
- epigenetic reader
- gene regulation
ASJC Scopus subject areas
- Molecular Medicine
- Cancer Research