Research Output

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Comment/debate
2019

Author Correction: Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data (Nature Reviews Cancer, (2019), 19, 5, (289-297), 10.1038/s41568-019-0133-9)

Rudin, C. M., Poirier, J. T., Byers, L. A., Dive, C., Dowlati, A., George, J., Heymach, J. V., Johnson, J. E., Lehman, J. M., MacPherson, D., Massion, P. P., Minna, J. D., Oliver, T. G., Quaranta, V., Sage, J., Thomas, R. K., Vakoc, C. R. & Gazdar, A. F., Jan 1 2019, In : Nature Reviews Cancer.

Research output: Contribution to journalComment/debate

Open Access
1 Scopus citations

Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359)

Kim, J., Hu, Z., Cai, L., Li, K., Choi, E., Faubert, B., Bezwada, D., Rodriguez-Canales, J., Villalobos, P., Lin, Y. F., Ni, M., Huffman, K. E., Girard, L., Byers, L. A., Unsal-Kacmaz, K., Peña, C. G., Heymach, J. V., Wauters, E., Vansteenkiste, J., Castrillon, D. H. & 6 others, Chen, B. P. C., Wistuba, I., Lambrechts, D., Xu, J., Minna, J. D. & DeBerardinis, R. J., May 16 2019, In : Nature. 569, 7756, p. E4

Research output: Contribution to journalComment/debate

Open Access

Correction: LCE: an open web portal to explore gene expression and clinical associations in lung cancer (Oncogene, (2019), 38, 14, (2551-2564), 10.1038/s41388-018-0588-2)

Cai, L., Lin, S. Y., Girard, L., Zhou, Y., Yang, L., Ci, B., Zhou, Q., Luo, D., Yao, B., Tang, H., Allen, J., Huffman, K., Gazdar, A. F., Heymach, J., Wistuba, I., Xiao, G., Minna, J. & Xie, Y., Jan 1 2019, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalComment/debate

2018

Diagnosis and management of pulmonary toxicity associated with cancer immunotherapy

Rashdan, S., Minna, J. D. & Gerber, D. E., Jun 1 2018, In : The Lancet Respiratory Medicine. 6, 6, p. 472-478 7 p.

Research output: Contribution to journalComment/debate

10 Scopus citations

Retraction notice to “Sun exposure related methylation in malignant and non-malignant skin lesions” [Cancer Letters 245/1-2 (2007) 112-120] (S0304383506000036) (10.1016/j.canlet.2005.12.042))

Sathyanarayana, U. G., Moore, A. Y., Li, L., Padar, A., Majmudar, K., Stastny, V., Makarla, P., Suzuki, M., Minna, J. D., Feng, Z. & Gazdar, A. F., Sep 28 2018, In : Cancer Letters. 432, 1 p.

Research output: Contribution to journalComment/debate

2016

Erratum: NRF2 regulates serine biosynthesis in non-small cell lung cancer (Nat. Genet. (2015) 47 (1475-1481))

Denicola, G. M., Chen, P. H., Mullarky, E., Sudderth, J. A., Hu, Z., Wu, D., Tang, H., Xie, Y., Asara, J. M., Huffman, K. E., Wistuba, I. I., Minna, J. D., Deberardinis, R. J. & Cantley, L. C., Mar 29 2016, In : Nature genetics. 48, 4, 1 p.

Research output: Contribution to journalComment/debate

4 Scopus citations
2015

Retraction notice to "Methylation of apoptosis related genes in the pathogenesis and prognosis of prostate cancer" [Cancer Lett. 242 (2) (2006) 222-230]

Suzuki, M., Shigematsu, H., Shivapurkar, N., Reddy, J., Miyajima, K., Takahashi, T., Gazdar, A. F. & Frenkel, E. P., Apr 28 2015, In : Cancer Letters. 360, 1, 1 p.

Research output: Contribution to journalComment/debate

2014

Erratum: Aberrant methylation profile of human malignant mesotheliomas and its relationship to SV40 infection (Oncogene (2005) 24 (1302-1308) DOI:10.1038/sj.onc.1208263)

Suzuki, M., Toyooka, S., Shivapurkar, N., Shigematsu, H., Miyajima, K., Takahashi, T., Stastny, V., Zern, A. L., Fujisawa, T., Pass, H. I., Carbone, M. & Gazdar, A. F., May 22 2014, In : Oncogene. 33, 21, 1 p.

Research output: Contribution to journalComment/debate

Retraction notice to "Aberrant methylation of Reprimo in lung cancer" [Lung Cancer 47 (2005) 309-314]

Suzuki, M., Shigematsu, H., Takahashi, T., Shivapurkar, N., Sathyanarayana, U. G., Iizasa, T., Fujisawa, T. & Gazdar, A. F., Aug 2014, In : Lung Cancer. 85, 2, 1 p.

Research output: Contribution to journalComment/debate

2013

Erratum: ASPP1, a common activator of TP53, is inactivated by aberrant methylation of its promoter in acute lymphoblastic leukemia (Oncogene (2013) 32 (803) DOI: 10.1038/onc.2012.593)

Agirre, X., Román-Gómez, J., Jiménez-Velasco, A., Garate, L., Montiel-Duarte, C., Navarro, G., Vázquez, I., Zalacain, M., Calasanz, M. J., Heiniger, A., Torres, A., Minna, J. D. & Prósper, F., Feb 7 2013, In : Oncogene. 32, 6, 1 p.

Research output: Contribution to journalComment/debate

Erratum: Differential inactivation of caspase-8 in lung cancers (Cancer Biology and Therapy (2002) 1, (65-69) DOI: 10.4161/cbt.1.1.45)

Shivapurkar, N., Toyooka, S., Eby, M. T., Huang, C. X., Sathyanarayana, U. G., Cunningham, H. T., Reddy, J. L., Brambilla, E., Takahashi, T., Minna, J. D., Chaudhary, P. M. & Gazdar, A. F., Nov 2013, In : Cancer Biology and Therapy. 14, 11, 1 p.

Research output: Contribution to journalComment/debate

Erratum: DNA methylation-associated inactivation of TGFβ-related genes, DRM/Gremlin, RUNX3, and HPP1 in human cancers (British Journal of Cancer (2005) 93 (1029-1037) DOI: 10.1038/sj.bjc.6602837)

Suzuki, M., Shigematsu, H., Shames, D. S., Sunaga, N., Takahashi, T., Shivapurkar, N., Iizasa, T., Frenkel, E. P., Minna, J. D., Fujisawa, T. & Gazdar, A. F., Dec 10 2013, In : British Journal of Cancer. 109, 12, 1 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Erratum: Aberrant promoter methylation of multiple genes during multistep pathogenesis of colorectal cancers(International Journal of Cancer (2012) 132 (499))

Takahashi, T., Shigematsu, H., Shivapurkar, N., Reddy, J., Zheng, Y., Feng, Z., Suzuki, M., Nomura, M., Augustus, M., Yin, J., Meltzer, S. J. & Gazdar, A. F., Jan 15 2013, In : International Journal of Cancer. 132, 2, 1 p.

Research output: Contribution to journalComment/debate

Erratum: Aberrant methylation of SPARC in human lung cancers(Expert Opinion on Investigational Drugs (2005) 92 (942-948) Doi: 10.1038/sj.bjc.6602376)

Suzuki, M., Hao, C., Takahashi, T., Shigematsu, H., Shivapurkar, N., Sathyanarayana, U. G., Iizasa, T., Fujisawa, T., Hiroshima, K. & Gazdar, A. F., Feb 19 2013, In : British Journal of Cancer. 108, 3, 1 p.

Research output: Contribution to journalComment/debate

Erratum: Aberrant methylation of reprimo in human malignancies(International Journal of Cancer (2013) 132 (498))

Takahashi, T., Suzuki, M., Shigematsu, H., Shivapurkar, N., Echebiri, C., Nomura, M., Stastny, V., Augustus, M., Wu, C. W., Wistuba, I. I., Meltzer, S. J. & Gazdar, A. F., Jan 15 2013, In : International Journal of Cancer. 132, 2, 1 p.

Research output: Contribution to journalComment/debate

Retraction: DNA methylation profiles of lymphoid and hematopoietic malignancies (Clinical Cancer Research (2004) 1)

Takahashi, T., Shivapurkar, N., Reddy, J., Shigematsu, H., Miyajima, K., Suzuki, M., Toyooka, S., Zöchbauer-Müller, S., Drach, J., Parikh, G., Zheng, Y., Feng, Z., Kroft, S. H., Timmons, C., McKenna, R. W. & Gazdar, A. F., Jan 1 2013, In : Clinical Cancer Research. 19, 1, 1 p.

Research output: Contribution to journalComment/debate

2012

Aberrant methylation to heparan sulfate glucosamine 3-O-sulfotransferase 2 genes as a biomarker in colorectal cancer (Anticancer Research (2010) 30, 12 (4811-4818))

Tokuyama, Y., Takahashi, T., Okumura, N., Nonaka, K., Kawaguchi, Y., Yamaguchi, K., Osada, S., Gazdar, A. & Yoshida, K., Dec 1 2012, In : Anticancer Research. 32, 12, 1 p.

Research output: Contribution to journalComment/debate

Aberrant methylation to heparan sulfate glucosamine 3-O-sulfotransferase 2 genes as a biomarker in colorectal cancer (Anticancer Research (2010) 30, 12 (4811-4818))

Tokuyama, Y., Takahashi, T., Okumura, N., Nonaka, K., Kawaguchi, Y., Yamaguchi, K., Osada, S., Gazdar, A. & Yoshida, K., Nov 1 2012, In : Anticancer Research. 32, 11, 1 p.

Research output: Contribution to journalComment/debate

A lung cancer molecular prognostic test ready for prime time

Xie, Y. & Minna, J. D., Mar 1 2012, In : The Lancet. 379, 9818, p. 785-787 3 p.

Research output: Contribution to journalComment/debate

11 Scopus citations
2011

Research highlights

Gazdar, A. F. & Zhang, Y. A., Aug 1 2011, In : Epigenomics. 3, 4, p. 405-406 2 p.

Research output: Contribution to journalComment/debate

Tyrosine kinase inhibitors and epidermal growth factor receptor (egfr) mutations in non-small cell lung cancer: To test or not to test?

Gazdar, A. F., May 1 2011, In : Medicine. 90, 3, p. 168-170 3 p.

Research output: Contribution to journalComment/debate

7 Scopus citations
2010

Towards patient-based cancer therapeutics

Schreiber, S. L., Shamji, A. F., Clemons, P. A., Hon, C., Koehler, A. N., Munoz, B., Palmer, M., Stern, A. M., Wagner, B. K., Powers, S., Lowe, S. W., Guo, X., Krasnitz, A., Sawey, E. T., Sordella, R., Stein, L., Trotman, L. C., Califano, A., Dalla-Favera, R., Ferrando, A. & 19 others, Iavarone, A., Pasqualucci, L., Silva, J., Stockwell, B. R., Hahn, W. C., Chin, L., DePinho, R. A., Boehm, J. S., Gopal, S., Huang, A., Root, D. E., Weir, B. A., Gerhard, D. S., Zenklusen, J. C., Roth, M. G., White, M. A., Minna, J. D., MacMillan, J. B. & Posner, B. A., Sep 1 2010, In : Nature biotechnology. 28, 9, p. 904-906 3 p.

Research output: Contribution to journalComment/debate

53 Scopus citations
2008

IP6K2 is a client for HSP90 and a target for cancer therapeutics development

Shames, D. S. & Minna, J. D., Feb 5 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 5, p. 1389-1390 2 p.

Research output: Contribution to journalComment/debate

17 Scopus citations
2007

Erratum: High-throughput oncogene mutation profiling in human cancer (Nature Genetics (2007) 39, (347-351))

Thomas, R. K., Baker, A. C., Debiasi, R. M., Winckler, W., Laframboise, T., Lin, W. M., Wang, M., Feng, W., Zander, T., MacConnaill, L. E., Lee, J. C., Nicoletti, R., Hatton, C., Goyette, M., Girard, L., Majmudar, K., Ziaugra, L., Wong, K. K., Gabriel, S., Beroukhim, R. & 33 others, Peyton, M., Barretina, J., Dutt, A., Emery, C., Greulich, H., Shah, K., Sasaki, H., Gazdar, A., Minna, J., Armstrong, S. A., Mellinghoff, I. K., Hodi, F. S., Dranoff, G., Mischel, P. S., Cloughesy, T. F., Nelson, S. F., Liau, L. M., Mertz, K., Rubin, M. A., Moch, H., Loda, M., Catalona, W., Fletcher, J., Signoretti, S., Kaye, F., Anderson, K. C., Demetri, G. D., Dummer, R., Wagner, S., Herlyn, M., Sellers, W. R., Meyerson, M. & Garraway, L. A., Apr 1 2007, In : Nature genetics. 39, 4, 1 p.

Research output: Contribution to journalComment/debate

3 Scopus citations
2006

Rapid screening for EGFR mutations: Pros and cons

Gazdar, A. F., Jan 1 2006, In : Cancer Journal. 12, 1, p. 17-18 2 p.

Research output: Contribution to journalComment/debate

2005

Erlotinib hydrochloride

Dowell, J., Minna, J. D. & Kirkpatrick, P., Jan 1 2005, In : Nature Reviews Drug Discovery. 4, 1, p. 13-14 2 p.

Research output: Contribution to journalComment/debate

100 Scopus citations

Erratum: Conserved transcription factor binding sites of cancer markers derived from primary lung adenocarcinoma microarrays (Nucleic Acids Research (2005) vol. 33 (409-421))

Yap, Y. L., Lam, D. C. L., Girard, L., Zhang, X. W., Hernandez, D., Gras, R., Wang, E., Chiu, S. W., Chung, L. P., Lam, W. K., Smith, D. K., Minna, J. D., Danchin, A. & Wong, M. P., Nov 3 2005, In : Nucleic acids research. 33, 8, 1 p.

Research output: Contribution to journalComment/debate

High resolution SNP arrays identify amplified regions in lung cancer

Weir, B., LaFramboise, T., Lin, M., Beroukhim, R., Garraway, L., Beheshti, J., Lee, J., Janne, P., Li, C., Sellers, W., Naoki, K., Richards, W., Sugarbaker, D., Chen, F., Rubin, M., Girard, L., Minna, J. & Christiani, D., Aug 1 2005, In : Cancer Biology and Therapy. 4, 8

Research output: Contribution to journalComment/debate

2003
144 Scopus citations
2002

Erratum: HLTF gene silencing in human colon cancer (Proceedings of the National Academy of Sciences of the United States of America (March 19, 2002) 99:7 (4562-4567))

Moinova, H. R., Wei-Dong-Chen, Shen, L., Smiraglia, D., Olechnowicz, J., Ravi, L., Kasturi, L., Myeroff, L., Plass, C., Parsons, R., Minna, J., Willson, J. K. V., Green, S. B., Issa, J. P. & Markowitz, S. D., Jun 25 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 13, 1 p.

Research output: Contribution to journalComment/debate

Inactivation of tumor suppressor genes by promoter methylation is important in the pathogenesis of pancreatic cancer

Fleming, J. B. & Minna, J. D., Jan 1 2002, In : Cancer Biology and Therapy. 1, 3, p. 297-299 3 p.

Research output: Contribution to journalComment/debate

Open Access
2 Scopus citations

Jettisoning the COXswain: Inhibitors of eicosanoids and lung cancer

Gazdar, A. F., Jan 1 2002, In : Clinical lung cancer. 3, 4, 1 p.

Research output: Contribution to journalComment/debate

2001

Erratum: PANORAMA: An integrated web-based sequence analysis tool and its role in gene discovery (Genomics (2000) 70 (300-306))

Pertsemlidis, A., Miller, B., Pande, A., Mittelman, D., Schilling, P., Wei, M. H., Lerman, M. I., Minna, J. D. & Garner, H. R., Aug 15 2001, In : Genomics. 77, 3, 1 p.

Research output: Contribution to journalComment/debate

Targeted therapies for killing tumor cells

Gazdar, A. F. & Minna, J. D., Aug 28 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 18, p. 10028-10030 3 p.

Research output: Contribution to journalComment/debate

15 Scopus citations
1997

Cigarettes, sex, and lung adenocarcinoma.

Gazdar, A. F. & Minna, J. D., Nov 5 1997, In : Journal of the National Cancer Institute. 89, 21, p. 1563-1565 3 p.

Research output: Contribution to journalComment/debate

Open Access
53 Scopus citations

Erratum: (The Journal of Clinical Investigation (October 1997) 100:8 (2133-2137))

Franklin, W. A., Gazdar, A. F., Haney, J., Wistuba, I. I., La Rosa, F. G., Kennedy, T., Ritchey, D. M. & Miller, Y. E., Jan 1 1997, In : Journal of Clinical Investigation. 100, 10, 1 p.

Research output: Contribution to journalComment/debate

2 Scopus citations
Open Access
17 Scopus citations
1996

Translational research comes of age

Minna, J. D. & Gazdar, A. F., Sep 26 1996, In : Nature medicine. 2, 9, p. 974-975 2 p.

Research output: Contribution to journalComment/debate

29 Scopus citations
1995

Allele-specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma.

Hung, J., Kishimoto, Y., Sugio, K., Virmani, A., McIntire, D. D., Minna, J. D. & Gazdar, A. F., Jun 28 1995, In : Journal of the American Medical Association. 273, 24, 1 p.

Research output: Contribution to journalComment/debate

40 Scopus citations
1992

Interaction-of the human papillomavirus type 16 E6 oncoprotein with wild- type and mutant human p53 proteins

Scheffner, M., Takahashi, T., Huibregtse, J. M., Minna, J. D. & Howley, P. M., Jan 1 1992, In : Journal of virology. 66, 8, p. 5100-5105 6 p.

Research output: Contribution to journalComment/debate

Open Access
117 Scopus citations
1985

Origin of human small cell lung cancer

Gazdar, A. F., Bunn, P. A., Minna, J. D. & Baylin, S. B., Jan 1 1985, In : Science. 229, 4714, p. 679-680 2 p.

Research output: Contribution to journalComment/debate

Open Access
31 Scopus citations