Pharmacology - Phillips Lab

Fingerprint Dive into the research topics where Pharmacology - Phillips Lab is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

Trypanosoma brucei brucei Medicine & Life Sciences
Anaphase-Promoting Complex-Cyclosome Medicine & Life Sciences
Mitosis Medicine & Life Sciences
Ornithine Decarboxylase Medicine & Life Sciences
Kinetochores Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Adenosylmethionine Decarboxylase Medicine & Life Sciences
Chromatids Medicine & Life Sciences

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Research Output 1987 2019

Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex

Uchikawa, E., Choi, E., Shang, G., Yu, H. & Bai, X., Aug 22 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
Insulin Receptor
Insulins
Chemical activation
Ligands
Dimers

Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling

Choi, E., Kikuchi, S., Gao, H., Brodzik, K., Nassour, I., Yopp, A. C., Singal, A., Zhu, H. & Yu, H., Dec 1 2019, In : Nature communications. 10, 1, 1473.

Research output: Contribution to journalArticle

Open Access
Dual Specificity Phosphatase 1
insulin
phosphatases
regulators
Insulin Receptor

Mps1 regulates spindle morphology through MCRS1 to promote chromosome alignment

Yang, H., Zhang, F., Huang, C. J., Liao, J., Han, Y., Hao, P., Chu, Y., Lu, X., Li, W., Yu, H. & Kang, J., Jan 1 2019, In : Molecular Biology of the Cell. 30, 9, p. 1060-1068 9 p.

Research output: Contribution to journalArticle

Kinetochores
Microtubules
Chromosomes
M Phase Cell Cycle Checkpoints
Anaphase