• 7790 Citations
  • 14 h-Index
19962019
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Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Research Output 1996 2019

  • 7790 Citations
  • 14 h-Index
  • 19 Article
  • 1 Chapter

Exome sequencing of drug-resistant clones for target identification

Han, T. & Nijhawan, D., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 175-187 13 p. (Methods in Molecular Biology; vol. 1888).

Research output: Chapter in Book/Report/Conference proceedingChapter

Exome
Clone Cells
Mutation
Pharmaceutical Preparations
Colorectal Neoplasms

Discovery of Cytochrome P450 4F11-Activated Inhibitors of Stearoyl Coenzyme A Desaturase

Winterton, S. E., Capota, E., Wang, X., Chen, H., Mallipeddi, P. L., Williams, N. S., Posner, B. A., Nijhawan, D. & Ready, J. M., Jan 12 2018, (Accepted/In press) In : Journal of Medicinal Chemistry.

Research output: Contribution to journalArticle

Stearoyl-CoA Desaturase
Cytochrome P-450 Enzyme System
Unsaturated Fatty Acids
Structure-Activity Relationship
Urea
51 Citations (Scopus)

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15

Han, T., Goralski, M., Gaskill, N., Capota, E., Kim, J., Ting, T. C., Xie, Y., Williams, N. S. & Nijhawan, D., Mar 16 2017, (Accepted/In press) In : Science. p. 1-21 21 p.

Research output: Contribution to journalArticle

RNA-Binding Proteins
Sulfonamides
Proteolysis
RNA Precursors
N-((5-bromo-2-thienyl)sulfonyl)-2,4-dichlorobenzamide
18 Citations (Scopus)

Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase

Theodoropoulos, P. C., Gonzales, S. S., Winterton, S. E., Rodriguez-Navas, C., McKnight, J. S., Morlock, L. K., Hanson, J. M., Cross, B., Owen, A. E., Duan, Y., Moreno, J. R., Lemoff, A., Mirzaei, H., Posner, B. A., Williams, N. S., Ready, J. M. & Nijhawan, D., Apr 1 2016, In : Nature Chemical Biology. 12, 4, p. 218-225 8 p.

Research output: Contribution to journalArticle

Stearoyl-CoA Desaturase
Benzothiazoles
Neoplasms
Cell Line
Cytochrome P-450 Enzyme System
14 Citations (Scopus)

Selective targeting of mutant adenomatous polyposis coli (APC) in colorectal cancer

Zhang, L., Theodoropoulos, P. C., Eskiocak, U., Wang, W., Moon, Y. A., Posner, B., Williams, N. S., Wright, W. E., Kim, S. B., Nijhawan, D., De Brabander, J. K. & Shay, J. W., Oct 19 2016, In : Science Translational Medicine. 8, 361, 361ra140.

Research output: Contribution to journalArticle

Adenomatous Polyposis Coli
Colorectal Neoplasms
Adenomatous Polyposis Coli Protein
Epithelial Cells
APC Genes