• 4188 Citations
  • 37 h-Index
1980 …2019
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Fingerprint Dive into the research topics where Mark A Lehrman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Dolichol Medicine & Life Sciences
Glycosylation Medicine & Life Sciences
Oligosaccharides Medicine & Life Sciences
Endoplasmic Reticulum Medicine & Life Sciences
Cricetulus Medicine & Life Sciences
Cricetinae Medicine & Life Sciences
Unfolded Protein Response Medicine & Life Sciences
Mannose Medicine & Life Sciences

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Research Output 1980 2019

  • 4188 Citations
  • 37 h-Index
  • 90 Article
  • 2 Chapter

A bioactive mammalian disaccharide associated with autoimmunity activates STING-TBK1-dependent immune response

Fermaintt, C. S., Sano, K., Liu, Z., Ishii, N., Seino, J., Dobbs, N., Suzuki, T., Fu, Y-X., Lehrman, M. A., Matsuo, I. & Yan, N., Dec 1 2019, In : Nature communications. 10, 1, 2377.

Research output: Contribution to journalArticle

Open Access
Disaccharides
activity (biology)
Autoimmunity
Autoimmune Diseases
Polysaccharides

Targeting STT3A-oligosaccharyltransferase with NGI-1 causes herpes simplex virus 1 dysfunction

Lu, H., Cherepanova, N. A., Gilmore, R., Contessa, J. N. & Lehrman, M. A., Jun 1 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 6, p. 6801-6812 12 p.

Research output: Contribution to journalArticle

Human Herpesvirus 1
Viruses
Glycosylation
Polysaccharides
Catalytic Domain

The Lec5 glycosylation mutant links homeobox genes with cholesterol and lipid-linked oligosaccharides

Lu, H., Sathe, A. A., Xing, C. & Lehrman, M. A., Feb 1 2019, In : Glycobiology. 29, 2, p. 106-109 4 p.

Research output: Contribution to journalArticle

Dolichol
Glycosylation
Homeobox Genes
Epigenomics
Cell Culture Techniques
1 Citation (Scopus)

Mammalian STT3A/B oligosaccharyltransferases segregate N-glycosylation at the translocon from lipid-linked oligosaccharide hydrolysis

Lu, H., Fermaintt, C. S., Cherepanova, N. A., Reid, G., Yan, N. & Lehrman, M. A., Sep 18 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 38, p. 9557-9562 6 p.

Research output: Contribution to journalArticle

Glycosylation
Hydrolysis
Oligosaccharides
lipid-linked oligosaccharides
dolichyl-diphosphooligosaccharide - protein glycotransferase
21 Citations (Scopus)

Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells

Lopez-Sambrooks, C., Shrimal, S., Khodier, C., Flaherty, D. P., Rinis, N., Charest, J. C., Gao, N., Zhao, P., Wells, L., Lewis, T. A., Lehrman, M. A., Gilmore, R., Golden, J. E. & Contessa, J. N., Oct 3 2016, (Accepted/In press) In : Nature Chemical Biology.

Research output: Contribution to journalArticle

Neoplasms
Glycosylation
Epidermal Growth Factor Receptor
Glycoproteins
Cell Line