• 70685 Citations
  • 119 h-Index
1984 …2019
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Fingerprint Dive into the research topics where Masashi Yanagisawa is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Endothelin-1 Medicine & Life Sciences
Endothelins Medicine & Life Sciences
Endothelin B Receptors Medicine & Life Sciences
Orexin Receptors Medicine & Life Sciences
Knockout Mice Medicine & Life Sciences
Endothelin A Receptors Medicine & Life Sciences
Neurons Medicine & Life Sciences
Sleep Medicine & Life Sciences

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Research Output 1984 2019

  • 70685 Citations
  • 119 h-Index
  • 447 Article
  • 3 Chapter
  • 2 Conference contribution

A new mouse model of GLUT1 deficiency syndrome exhibits abnormal sleep-wake patterns and alterations of glucose kinetics in the brain

Furuse, T., Mizuma, H., Hirose, Y., Kushida, T., Yamada, I., Miura, I., Masuya, H., Funato, H., Yanagisawa, M., Onoe, H. & Wakana, S., Sep 12 2019, In : Disease models & mechanisms. 12, 9

Research output: Contribution to journalArticle

Open Access
Facilitative Glucose Transport Proteins
Brain
Sleep
Glucose
Electroencephalography

A novel rearrangement reaction of morphinan to arylmorphan skeletons and the pharmacologies of arylmorphan derivatives

Yata, M., Kutsumura, N., Nagumo, Y., Yamamoto, N., Saitoh, T., Ishikawa, Y., Irukayama-Tomobe, Y., Yanagisawa, M. & Nagase, H., Jan 1 2019, In : Heterocycles. p. 134-144 11 p.

Research output: Contribution to journalArticle

Morphinans
Opioid Receptors
Skeleton
Nitrogen
Orexin Receptors

Differential Roles of Each Orexin Receptor Signaling in Obesity

Kakizaki, M., Tsuneoka, Y., Takase, K., Kim, S. J., Choi, J., Ikkyu, A., Abe, M., Sakimura, K., Yanagisawa, M. & Funato, H., Oct 25 2019, In : iScience. 20, p. 1-13 13 p.

Research output: Contribution to journalArticle

Open Access
Orexin Receptors
Obesity
Endocrinology
1 Citation (Scopus)

Essential structure of orexin 1 receptor antagonist YNT-707, part III: Role of the 14-hydroxy and the 3-methoxy groups in antagonistic activity toward the orexin 1 receptor in YNT-707 derivatives lacking the 4,5-epoxy ring

Yamamoto, N., Ohrui, S., Okada, T., Saitoh, T., Kutsumura, N., Nagumo, Y., Irukayama-Tomobe, Y., Ogawa, Y., Ishikawa, Y., Watanabe, Y., Hayakawa, D., Gouda, H., Yanagisawa, M. & Nagase, H., Jan 1 2019, In : Bioorganic and Medicinal Chemistry.

Research output: Contribution to journalArticle

Orexin Receptors
Morphinans
Derivatives
Amides
Assays

Essential structure of orexin 1 receptor antagonist YNT-707, Part IV: The role of D-ring in 4,5-epoxymorphinan on the orexin 1 receptor antagonistic activity

Saitoh, T., Seki, K., Nakajima, R., Yamamoto, N., Kutsumura, N., Nagumo, Y., Irukayama-Tomobe, Y., Ogawa, Y., Ishikawa, Y., Tanimura, R., Yanagisawa, M. & Nagase, H., Jan 1 2019, In : Bioorganic and Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

Morphinans
Orexin Receptors
Sulfonamides
Scaffolds
Amides