• 69626 Citations
  • 119 h-Index
1984 …2019
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  • 6 Similar Profiles
Endothelin-1 Medicine & Life Sciences
Endothelins Medicine & Life Sciences
Endothelin B Receptors Medicine & Life Sciences
Orexin Receptors Medicine & Life Sciences
Knockout Mice Medicine & Life Sciences
Endothelin A Receptors Medicine & Life Sciences
Neurons Medicine & Life Sciences
Endothelin Receptors Medicine & Life Sciences

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Research Output 1984 2019

  • 69626 Citations
  • 119 h-Index
  • 441 Article
  • 3 Chapter
  • 2 Conference contribution

Essential structure of orexin 1 receptor antagonist YNT-707, part III: Role of the 14-hydroxy and the 3-methoxy groups in antagonistic activity toward the orexin 1 receptor in YNT-707 derivatives lacking the 4,5-epoxy ring

Yamamoto, N., Ohrui, S., Okada, T., Saitoh, T., Kutsumura, N., Nagumo, Y., Irukayama-Tomobe, Y., Ogawa, Y., Ishikawa, Y., Watanabe, Y., Hayakawa, D., Gouda, H., Yanagisawa, M. & Nagase, H., Jan 1 2019, In : Bioorganic and Medicinal Chemistry.

Research output: Contribution to journalArticle

Orexin Receptors

Toward the mysteries of sleep

Yanagisawa, M., Jan 1 2019, In : Keio Journal of Medicine. 68, 1, 1 p.

Research output: Contribution to journalArticle

Open Access

Ablation of central serotonergic neurons decreased REM sleep and attenuated arousal response

Iwasaki, K., Komiya, H., Kakizaki, M., Miyoshi, C., Abe, M., Sakimura, K., Funato, H. & Yanagisawa, M., Aug 7 2018, In : Frontiers in Neuroscience. 12, AUG, 535.

Research output: Contribution to journalArticle

Serotonergic Neurons
REM Sleep
2 Citations (Scopus)

Acute pressor response to psychosocial stress is dependent on endothelium-derived endothelin-1

Fox, B. M., Becker, B. K., Loria, A. S., Hyndman, K. A., Jin, C., Clark, H., Johns, R., Yanagisawa, M., Pollock, D. M. & Pollock, J. S., Feb 1 2018, In : Journal of the American Heart Association. 7, 4, e007863.

Research output: Contribution to journalArticle

Vascular Endothelium
Knockout Mice
Endothelin A Receptors

A single phosphorylation site of SIK3 regulates daily sleep amounts and sleep need in mice

Honda, T., Fujiyama, T., Miyoshi, C., Ikkyu, A., Hotta-Hirashima, N., Kanno, S., Mizuno, S., Sugiyama, F., Takahashi, S., Funato, H. & Yanagisawa, M., Oct 9 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 41, p. 10458-10463 6 p.

Research output: Contribution to journalArticle

Eye Movements
Disorders of Excessive Somnolence
Sequence Deletion