• 707 Citations
  • 14 h-Index
20092019
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Fingerprint Dive into the research topics where Xiaochun Li is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Cholesterol Medicine & Life Sciences
Sterols Medicine & Life Sciences
Proteins Medicine & Life Sciences
Peptide Hydrolases Medicine & Life Sciences
Cryoelectron Microscopy Medicine & Life Sciences
S 6 Medicine & Life Sciences
human EBP protein Medicine & Life Sciences
Binding Sites Medicine & Life Sciences

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Research Output 2009 2019

  • 707 Citations
  • 14 h-Index
  • 18 Article
  • 2 Letter
  • 1 Review article

Cryo-EM structure of oxysterol-bound human Smoothened coupled to a heterotrimeric Gi

Qi, X., Liu, H., Thompson, B., McDonald, J., Zhang, C. & Li, X., Jan 1 2019, (Accepted/In press) In : Nature.

Research output: Contribution to journalLetter

Veratrum Alkaloids
Hedgehog Proteins
Gi-Go GTP-Binding Protein alpha Subunits
Cryoelectron Microscopy
Immunoglobulin Fab Fragments

Structural basis for human sterol isomerase in cholesterol biosynthesis and multidrug recognition

Long, T., Hassan, A., Thompson, B. M., McDonald, J. G., Wang, J. & Li, X., Dec 1 2019, In : Nature communications. 10, 1, 2452.

Research output: Contribution to journalArticle

Open Access
human EBP protein
Neoplasm Drug Resistance
Steroid Isomerases
Chondrodysplasia Punctata
Molecular Docking Simulation
6 Citations (Scopus)

Structural basis for PtdInsP2-mediated human TRPML1 regulation

Fine, M., Schmiege, P. & Li, X., Dec 1 2018, In : Nature Communications. 9, 1, 4192.

Research output: Contribution to journalArticle

Phosphatidylinositol 4,5-Diphosphate
lipids
calcium
Lipids
efflux
30 Citations (Scopus)

Structures of human Patched and its complex with native palmitoylated sonic hedgehog

Qi, X., Schmiege, P., Coutavas, E., Wang, J. & Li, X., Aug 2 2018, In : Nature. 560, 7716, p. 128-132 5 p.

Research output: Contribution to journalLetter

Hedgehogs
Cryoelectron Microscopy
Palmitates
Oncogene Proteins
Sterols
1 Citation (Scopus)

The regulatory mechanism of mammalian TRPMLs revealed by cryo-EM

Schmiege, P., Fine, M. & Li, X., Jan 1 2018, (Accepted/In press) In : FEBS Journal.

Research output: Contribution to journalArticle

Transient Receptor Potential Channels
S 6
Conformations
Viperidae
Dilatation