Mutation of the conserved N-terminal cysteine (Cys92) of human presenilin 1 causes increased Aβ42 secretion in mammalian cells but impaired Notch/lin-12 signalling in C. elegans

Mei Zhang Dong Mei Zhang, D. Levitan, G. Yu, M. Nishimura, F. Chen, A. Tandon, T. Kawarai, S. Arawaka, A. Supala, Y. Q. Song, E. Rogaeva, Y. Liang, E. Holmes, P. Milman, C. Sato, L. Zhang, P. St George-Hyslop

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Medicine & Life Sciences