Research Output

2002

Speckle experiments in random lasers

Van Soest, G., Poelwijk, F. J. & Lagendijk, A., Apr 1 2002, In : Physical Review E - Statistical, Nonlinear, and Soft Matter Physics. 65, 4, p. 046603/1-046603/5 046603.

Research output: Contribution to journalArticle

13 Scopus citations

Structural basis of gating by the outer membrane transporter FecA

Ferguson, A. D., Chakraborty, R., Smith, B. S., Esser, L., Van Der Helm, D. & Deisenhofer, J., Mar 1 2002, In : Science. 295, 5560, p. 1715-1719 5 p.

Research output: Contribution to journalArticle

287 Scopus citations
163 Scopus citations

Structure of the LDL receptor extracellular domain at endosomal pH

Rudenko, G., Henry, L., Henderson, K., Ichtchenko, K., Brown, M. S., Goldstein, J. L. & Deisenhofer, J., Dec 20 2002, In : Science. 298, 5602, p. 2353-2358 6 p.

Research output: Contribution to journalArticle

337 Scopus citations

TonB-dependent receptors - Structural perspectives

Ferguson, A. D. & Deisenhofer, J., Oct 11 2002, In : Biochimica et Biophysica Acta - Biomembranes. 1565, 2, p. 318-332 15 p.

Research output: Contribution to journalReview article

98 Scopus citations

Uncoupling Kapβ2 substrate dissociation and ran binding

Chook, Y. M., Jung, A., Rosen, M. K. & Blobel, G., Jun 4 2002, In : Biochemistry. 41, 22, p. 6955-6966 12 p.

Research output: Contribution to journalArticle

43 Scopus citations
2001

An analysis of the interactions between the Sem-5 SH3 domain and its ligands using molecular dynamics, free energy calculations, and sequence analysis

Wang, W., Lim, W. A., Jakalian, A., Wang, J., Wang, J., Luo, R., Bayly, C. I. & Kollman, P. A., Oct 8 2001, In : Journal of the American Chemical Society. 123, 17, p. 3986-3994 9 p.

Research output: Contribution to journalArticle

121 Scopus citations

APC2 cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex

Tang, Z., Li, B., Bharadwaj, R., Zhu, H., Özkan, E., Hakala, K., Deisenhofer, J. & Yu, H., 2001, In : Molecular biology of the cell. 12, 12, p. 3839-3851 13 p.

Research output: Contribution to journalArticle

136 Scopus citations

Automatic parameterization of force field by systematic search and genetic algorithms

Wang, J. & Kollman, P. A., Sep 1 2001, In : Journal of Computational Chemistry. 22, 12, p. 1219-1228 10 p.

Research output: Contribution to journalArticle

93 Scopus citations
51 Scopus citations

Conformational stabilization and crystallization of the SecA translocation ATPase from Bacillus subtilis

Weinkauf, S., Hunt, J. F., Scheuring, J., Henry, L., Fak, J., Oliver, D. B. & Deisenhofer, J., Apr 25 2001, In : Acta Crystallographica Section D: Biological Crystallography. 57, 4, p. 559-565 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia

Devriendt, K., Kim, A. S., Mathijs, G., Frints, S. G. M., Schwartz, M., Van Den Oord, J. J., Verhoef, G. E. G., Boogaerts, M. A., Fryns, J. P., You, D., Rosen, M. K. & Vandenberghe, P., Mar 20 2001, In : Nature genetics. 27, 3, p. 313-317 5 p.

Research output: Contribution to journalArticle

319 Scopus citations

Crystal structure of a T cell receptor Vα11 (AV11S5) domain: New canonical forms for the first and second complementarity determining regions

Machius, M., Cianga, P., Deisenhofer, J. & Ward, E. S., Jul 20 2001, In : Journal of Molecular Biology. 310, 4, p. 689-698 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Crystal structures of mitochondrial processing peptidase reveal the mode for specific cleavage of import signal sequences

Taylor, A. B., Smith, B. S., Kitada, S., Kojima, K., Miyaura, H., Otwinowski, Z., Ito, A. & Deisenhofer, J., Aug 11 2001, In : Structure. 9, 7, p. 615-625 11 p.

Research output: Contribution to journalArticle

164 Scopus citations
176 Scopus citations

Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice

Gupta, P., Soyombo, A. A., Atashband, A., Wisniewski, K. E., Shelton, J. M., Richardson, J. A., Hammer, R. E. & Hofmann, S. L., Nov 20 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 24, p. 13566-13571 6 p.

Research output: Contribution to journalArticle

205 Scopus citations

Dynamics of a random laser above threshold

Van Soest, G., Poelwijk, F. J., Sprik, R. & Lagendijk, A., Feb 19 2001, In : Physical Review Letters. 86, 8, p. 1522-1525 4 p.

Research output: Contribution to journalArticle

72 Scopus citations

Embryonic neuronal death due to neurotrophin and neurotransmitter deprivation occurs independent of Apaf-1

Honarpour, N., Tabuchi, K., Stark, J. M., Hammer, R. E., Südhof, T. C., Parada, L. F., Wang, X., Richardson, J. A. & Herz, J., Sep 6 2001, In : Neuroscience. 106, 2, p. 263-274 12 p.

Research output: Contribution to journalArticle

22 Scopus citations

Flipping a switch

Buck, M. & Rosen, M. K., Mar 23 2001, In : Science. 291, 5512, p. 2329-2330 2 p.

Research output: Contribution to journalShort survey

11 Scopus citations

Global disruption of the WASP autoinhibited structure on Cdc42 binding. Ligand displacement as a novel method for monitoring amide hydrogen exchange

Buck, M., Xu, W. & Rosen, M. K., Nov 27 2001, In : Biochemistry. 40, 47, p. 14115-14122 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress

Meira, L. B., Devaraj, S., Kisby, G. E., Burns, D. K., Daniel, R. L., Hammer, R. E., Grundy, S. M., Jialal, I. & Friedberg, E. C., Jul 15 2001, In : Cancer Research. 61, 14, p. 5552-5557 6 p.

Research output: Contribution to journalArticle

141 Scopus citations

Proteins

Deisenhofer, J. & Smith, J. L., Dec 1 2001, In : Current Opinion in Structural Biology. 11, 6, p. 701-702 2 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Quantitative assays for GTPase-activating proteins

Ross, E. M., 2001, In : Methods in Enzymology. 344, p. 601-617 17 p.

Research output: Contribution to journalArticle

25 Scopus citations

Quench-flow kinetic measurement of individual reactions of G-protein-catalyzed GTPase cycle

Mukhopadhyay, S. & Ross, E. M., 2001, In : Methods in Enzymology. 344, p. 350-369 20 p.

Research output: Contribution to journalArticle

11 Scopus citations

Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development

Freiman, R. N., Albright, S. R., Zheng, S., Sha, W. C., Hammer, R. E. & Tjian, R., Sep 14 2001, In : Science. 293, 5537, p. 2084-2087 4 p.

Research output: Contribution to journalArticle

159 Scopus citations

RGSZ1 and Ret RGS: Two of several splice variants from the gene RGS20

Barker, S. A., Wang, J., Sierra, D. A. & Ross, E. M., Dec 2001, In : Genomics. 78, 3, p. 223-229 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation

Matsuda, M., Korn, B. S., Hammer, R. E., Moon, Y. A., Komuro, R., Horton, J. D., Goldstein, J. L., Brown, M. S. & Shimomura, I., May 15 2001, In : Genes and Development. 15, 10, p. 1206-1216 11 p.

Research output: Contribution to journalArticle

230 Scopus citations

Structural mechanism for statin inhibition of HMG-CoA reductase

Istvan, E. S. & Deisenhofer, J., May 11 2001, In : Science. 292, 5519, p. 1160-1164 5 p.

Research output: Contribution to journalArticle

953 Scopus citations
51 Scopus citations

The Role of PTF1-P48 in Pancreatic Acinar Gene Expression

Rose, S. D., Swift, G. H., Peyton, M. J., Hammer, R. E. & MacDonald, R. J., Nov 23 2001, In : Journal of Biological Chemistry. 276, 47, p. 44018-44026 9 p.

Research output: Contribution to journalArticle

82 Scopus citations

Tie2-Cre transgenic mice: A new model for endothelial cell-lineage analysis in vivo

Kisanuki, Y. Y., Hammer, R. E., Miyazaki, J. I., Williams, S. C., Richardson, J. A. & Yanagisawa, M., Feb 15 2001, In : Developmental Biology. 230, 2, p. 230-242 13 p.

Research output: Contribution to journalArticle

797 Scopus citations
599 Scopus citations

WASP recruitment to the T cell:APC contact site occurs independently of Cdc42 activation

Cannon, J. L., Labno, C. M., Bosco, G., Seth, A., McGavin, M. H. K., Siminovitch, K. A., Rosen, M. K. & Burkhardt, J. K., Jan 1 2001, In : Immunity. 15, 2, p. 249-259 11 p.

Research output: Contribution to journalArticle

130 Scopus citations
2000

Adult Apaf-1-deficient mice exhibit male infertility

Honarpour, N., Du, C., Richardson, J. A., Hammer, R. E., Wang, X. & Herz, J., Feb 15 2000, In : Developmental Biology. 218, 2, p. 248-258 11 p.

Research output: Contribution to journalArticle

168 Scopus citations

A molecular pathway for light-dependent photoreceptor apoptosis in Drosophila

Kiselev, A., Socolich, M., Vinós, J., Hardy, R. W., Zuker, C. S. & Ranganathan, R., Jan 1 2000, In : Neuron. 28, 1, p. 139-152 14 p.

Research output: Contribution to journalArticle

Open Access
197 Scopus citations

Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein

Kim, A. S., Kakalis, L. T., Abdul-Manan, N., Liu, G. A. & Rosen, M. K., Mar 9 2000, In : Nature. 404, 6774, p. 151-158 8 p.

Research output: Contribution to journalArticle

562 Scopus citations

Cloning and characterization of the Dictyostelium discoideum cycloartenol synthase cDNA

Godzina, S. M., Lovato, M. A., Meyer, M. M., Foster, K. A., Wilson, W. K., Gu, W., De Hostos, E. L. & Matsuda, S. P. T., Jan 1 2000, In : Lipids. 35, 3, p. 249-255 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Crystal structure of Rab geranylgeranyltransferase at 2.0 Å resolution

Zhang, H., Seabra, M. C. & Deisenhofer, J., Mar 1 2000, In : Structure. 8, 3, p. 241-251 11 p.

Research output: Contribution to journalArticle

94 Scopus citations

Crystal structure of the catalytic portion of human HMG-CoA reductase: Insights into regulation of activity and catalysis

Istvan, E. S., Palnitkar, M., Buchanan, S. K. & Deisenhofer, J., Mar 1 2000, In : EMBO Journal. 19, 5, p. 819-830 12 p.

Research output: Contribution to journalArticle

211 Scopus citations

Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice

Shimomura, I., Matsuda, M., Hammer, R. E., Bashmakov, Y., Brown, M. S. & Goldstein, J. L., Jan 1 2000, In : Molecular cell. 6, 1, p. 77-86 10 p.

Research output: Contribution to journalArticle

Open Access
651 Scopus citations

Detection of very weak side chain-main chain hydrogen bonding interactions in medium-size 13C/15N-labeled proteins by sensitivity- enhanced NMR spectroscopy

Liu, A., Hu, W., Majumdar, A., Rosen, M. K. & Patel, D. J., Jan 1 2000, In : Journal of Biomolecular NMR. 17, 1, p. 79-82 4 p.

Research output: Contribution to journalArticle

14 Scopus citations

Disruption of ECE-1 and ECE-2 reveals a role for endothelin-converting enzyme-2 in murine cardiac development

Yanagisawa, H., Hammer, R. E., Richardson, J. A., Emoto, N., Clay Williams, S., Takeda, S. I., Clouthier, D. E. & Yanagisawa, M., May 2000, In : Journal of Clinical Investigation. 105, 10, p. 1373-1382 10 p.

Research output: Contribution to journalArticle

Open Access
163 Scopus citations

DNA photolyases and cryptochromes

Deisenhofer, J., Aug 30 2000, In : Mutation Research - DNA Repair. 460, 3-4, p. 143-149 7 p.

Research output: Contribution to journalArticle

64 Scopus citations
861 Scopus citations

High-level rearrangement and transcription of yeast artificial chromosome-based mouse Igκ transgenes containing distal regions of the contig

Li, S., Hammer, R. E., George-Raizen, J. B., Meyers, K. C. & Garrard, W. T., Jan 15 2000, In : Journal of Immunology. 164, 2, p. 812-824 13 p.

Research output: Contribution to journalArticle

8 Scopus citations
3117 Scopus citations

Interhelical hydrogen bonding drives strong interactions in membrane proteins

Zhou, F. X., Cocco, M. J., Russ, W. P., Brunger, A. T. & Engelman, D. M., Feb 1 2000, In : Nature Structural Biology. 7, 2, p. 154-160 7 p.

Research output: Contribution to journalArticle

340 Scopus citations

Mechanistic studies of affinity modulation

Rosen, M. K., Amos, C. D. & Wandless, T. J., Dec 6 2000, In : Journal of the American Chemical Society. 122, 48, p. 11979-11982 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

NMR detection of side chain-side chain hydrogen bonding interactions in 13C/15N-labeled proteins

Liu, A., Hu, W., Majumdar, A., Rosen, M. K. & Patel, D. J., Jan 1 2000, In : Journal of biomolecular NMR. 17, 4, p. 305-310 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Photon correlation spectroscopy: X rays versus visible light

Riese, D. O., Vos, W. L., Wegdam, G. H., Poelwijk, F. J., Abernathy, D. L. & Grübel, G., Jan 1 2000, In : Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics. 61, 2, p. 1676-1680 5 p.

Research output: Contribution to journalArticle

41 Scopus citations