Research Output

Article

A single nucleotide polymorphism in the MDM2 gene disrupts the oscillation of p53 and MDM2 levels in cells

Hu, W., Feng, Z., Ma, L., Wagner, J., Rice, J. J., Stolovitzky, G. & Levine, A. J., Mar 15 2007, In : Cancer Research. 67, 6, p. 2757-2765 9 p.

Research output: Contribution to journalArticle

84 Scopus citations

Assay of protein in the presence of high concentrations of sulfhydryl compounds

Ross, E. & Schatz, G., Jul 1973, In : Analytical Biochemistry. 54, 1, p. 304-306 3 p.

Research output: Contribution to journalArticle

262 Scopus citations

Assessing the performance of MM/PBSA and MM/GBSA methods. 3. the impact of force fields and ligand charge models

Xu, L., Sun, H., Li, Y., Wang, J. & Hou, T., Jul 18 2013, In : Journal of Physical Chemistry B. 117, 28, p. 8408-8421 14 p.

Research output: Contribution to journalArticle

274 Scopus citations
1056 Scopus citations
409 Scopus citations

Assessment of linear finite-difference poisson-boltzmann solvers

Wang, J. U. N. & Luo, R. A. Y., Jun 1 2010, In : Journal of Computational Chemistry. 31, 8, p. 1689-1698 10 p.

Research output: Contribution to journalArticle

57 Scopus citations

A structural basis of the interactions between leucine-rich repeats and protein ligands

Kobe, B. & Deisenhofer, J., Jan 1 1995, In : Nature. 374, 6518, p. 183-186 4 p.

Research output: Contribution to journalArticle

547 Scopus citations

A substitution mutation in a conserved domain of mammalian acetate-dependent acetyl CoA synthetase 2 results in destabilized protein and impaired HIF-2 signaling

Nagati, J. S., Xu, M., Garcia, T., Comerford, S. A., Hammer, R. E. & Garcia, J. A., 2019, In : PloS one. 14, 11, e0225105.

Research output: Contribution to journalArticle

Open Access

Atherogenesis in transgenic mice expressing human apolipoprotein(a)

Lawn, R. M., Wade, D. P., Hammer, R. E., Chiesa, G., Verstuyft, J. G. & Rubin, E. M., Jan 1 1992, In : Nature. 360, 6405, p. 670-672 3 p.

Research output: Contribution to journalArticle

241 Scopus citations

ATP-dependent regulation of flagellar adenylylcyclase in gametes of Chlamydomonas reinhardtii

Zhang, Y., Ross, E. M. & Snell, W. J., Dec 1 1991, In : Journal of Biological Chemistry. 266, 34, p. 22954-22959 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

A transgene coding for a human insulin analog has a mitogenic effect on murine embryonic β cells

Vincent, M. T., Carroll, R. J., Hammer, R. E., Chan, S. J., Guz, Y., Steiner, D. F. & Teitelman, G., Jul 3 1995, In : Proceedings of the National Academy of Sciences of the United States of America. 92, 14, p. 6239-6243 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

A truncation mutation in the avian β-adrenergic receptor causes agonist-induced internalization and GTP-sensitive agonist binding characteristic of mammalian receptors

Hertel, C., Nunnally, M. H., Wong, S. K. F., Murphy, E. A., Ross, E. M. & Perkins, J. P., Nov 12 1990, In : Journal of Biological Chemistry. 265, 29, p. 17988-17994 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

A Two-Enzyme Adaptive Unit within Bacterial Folate Metabolism

Schober, A. F., Mathis, A. D., Ingle, C., Park, J. O., Chen, L., Rabinowitz, J. D., Junier, I., Rivoire, O. & Reynolds, K. A., Jun 11 2019, In : Cell Reports. 27, 11, p. 3359-3370.e7

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

A two-state allosteric model for autoinhibition rationalizes WASP signal integration and targeting

Buck, M., Xu, W. & Rosen, M. K., Apr 23 2004, In : Journal of Molecular Biology. 338, 2, p. 271-285 15 p.

Research output: Contribution to journalArticle

44 Scopus citations

Autoimmune epididymoorchitis is essential to the pathogenesis of male-specific spondylarthritis in HLA-B27-transgenic rats

Taurog, J. D., Rival, C., Van Duivenvoorde, L. M., Satumtira, N., Dorris, M. L., Sun, M., Shelton, J. M., Richardson, J. A., Hamra, F. K., Hammer, R. E. & Tung, K. S. K., Aug 1 2012, In : Arthritis and rheumatism. 64, 8, p. 2518-2528 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein

Kim, A. S., Kakalis, L. T., Abdul-Manan, N., Liu, G. A. & Rosen, M. K., Mar 9 2000, In : Nature. 404, 6774, p. 151-158 8 p.

Research output: Contribution to journalArticle

562 Scopus citations

Autoinhibition regulates cellular localization and actin assembly activity of the diaphanous-related formins FRLα and mDia1

Seth, A., Otomo, C. & Rosen, M. K., Aug 28 2006, In : Journal of Cell Biology. 174, 5, p. 701-713 13 p.

Research output: Contribution to journalArticle

99 Scopus citations

Automated docking of peptides and proteins by genetic algorithm

Wang, J., Hou, T., Chen, L. & Xu, X., Jan 18 1999, In : Chemometrics and Intelligent Laboratory Systems. 45, 1-2, p. 281-286 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Automated docking of peptides and proteins by using a genetic algorithm combined with a tabu search

Hou, T., Wang, J., Chen, L. & Xu, X., Jan 1 1999, In : Protein Engineering. 12, 8, p. 639-647 9 p.

Research output: Contribution to journalArticle

61 Scopus citations

Automatic atom type and bond type perception in molecular mechanical calculations

Wang, J., Wang, W., Kollman, P. A. & Case, D. A., Oct 1 2006, In : Journal of Molecular Graphics and Modelling. 25, 2, p. 247-260 14 p.

Research output: Contribution to journalArticle

2291 Scopus citations

Automatic parameterization of force field by systematic search and genetic algorithms

Wang, J. & Kollman, P. A., Sep 1 2001, In : Journal of Computational Chemistry. 22, 12, p. 1219-1228 10 p.

Research output: Contribution to journalArticle

93 Scopus citations

Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis

Wang, S. S., Gu, Y. F., Wolff, N., Stefanius, K., Christie, A., Dey, A., Hammer, R. E., Xie, X-J., Rakheja, D., Pedrosa, I., Carroll, T. J., McKay, R. M., Kapur, P. & Brugarolas, J. B., Nov 18 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 46, p. 16538-16543 6 p.

Research output: Contribution to journalArticle

74 Scopus citations

beta-Adrenergic receptors and regulatory GTP-binding proteins: reconstitution of coupling in phospholipid vesicles.

Asano, T., Brandt, D. R., Pedersen, S. E. & Ross, E. M., Jan 1 1985, In : Advances in cyclic nucleotide and protein phosphorylation research. 19, p. 47-56 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Beyond Molecular Codes: Simple Rules to Wire Complex Brains

Hassan, B. A. & Hiesinger, P. R., Oct 8 2015, In : Cell. 163, 2, p. 285-291 7 p.

Research output: Contribution to journalArticle

38 Scopus citations
51 Scopus citations

Biomolecular condensates: organizers of cellular biochemistry

Banani, S. F., Lee, H. O., Hyman, A. A. & Rosen, M. K., Feb 22 2017, (Accepted/In press) In : Nature Reviews Molecular Cell Biology.

Research output: Contribution to journalArticle

758 Scopus citations

Bipartite gating in the outer membrane protein FecA

Van der Helm, D., Chakraborty, R., Ferguson, A. D., Smith, B. S., Esser, L. & Deisenhofer, J., Aug 1 2002, In : Biochemical Society Transactions. 30, 4, p. 708-710 3 p.

Research output: Contribution to journalArticle

10 Scopus citations

Blockade of MCU-Mediated Ca 2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation

Tomar, D., Jaña, F., Dong, Z., Quinn, W. J., Jadiya, P., Breves, S. L., Daw, C. C., Srikantan, S., Shanmughapriya, S., Nemani, N., Carvalho, E., Tripathi, A., Worth, A. M., Zhang, X., Razmpour, R., Seelam, A., Rhode, S., Mehta, A. V., Murray, M., Slade, D. & 12 others, Ramirez, S. H., Mishra, P., Gerhard, G. S., Caplan, J., Norton, L., Sharma, K., Rajan, S., Balciunas, D., Wijesinghe, D. S., Ahima, R. S., Baur, J. A. & Madesh, M., Mar 26 2019, In : Cell Reports. 26, 13, p. 3709-3725.e7

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Blunted feedback suppression of SREBP processing by dietary cholesterol in transgenic mice expressing sterol-resistant SCAP(D443N)

Korn, B. S., Shimomura, L., Bashmakov, Y., Hammer, R. E., Horton, J. D., Goldstein, J. L. & Brown, M. S., Dec 15 1998, In : Journal of Clinical Investigation. 102, 12, p. 2050-2060 11 p.

Research output: Contribution to journalArticle

Open Access
52 Scopus citations

Breaking down cellulose fibrils with a mid-infrared laser

Domin, D., Man, V. H., Van-Oanh, N. T., Wang, J., Kawasaki, T., Derreumaux, P. & Nguyen, P. H., Oct 1 2018, In : Cellulose. 25, 10, p. 5553-5568 16 p.

Research output: Contribution to journalArticle

1 Scopus citations

Building a morbidostat: An automated continuous-culture device for studying bacterial drug resistance under dynamically sustained drug inhibition

Toprak, E., Veres, A., Yildiz, S., Pedraza, J. M., Chait, R., Paulsson, J. & Kishony, R., Feb 2013, In : Nature Protocols. 8, 3, p. 555-567 13 p.

Research output: Contribution to journalArticle

62 Scopus citations

Carboxyl-terminal domains in the avian β1-adrenergic receptor that regulate agonist-promoted endocytosis

Parker, E. M., Swigart, P., Nunnally, M. H., Perkins, J. P. & Ross, E. M., Jan 1 1995, In : Journal of Biological Chemistry. 270, 12, p. 6482-6487 6 p.

Research output: Contribution to journalArticle

29 Scopus citations

Carboxyl-terminal fragments of phospholipase C-β1 with intrinsic G(q) GTPase-activating protein (GAP) activity

Paulssen, R. H., Woodson, J., Liu, Z. & Ross, E. M., Nov 6 1996, In : Journal of Biological Chemistry. 271, 43, p. 26622-26629 8 p.

Research output: Contribution to journalArticle

58 Scopus citations

Cardiomyocyte-Specific Endothelin A Receptor Knockout Mice Have Normal Cardiac Function and an Unaltered Hypertrophic Response to Angiotensin II and Isoproterenol

Kedzierski, R. M., Grayburn, P. A., Kisanuki, Y. Y., Williams, C. S., Hammer, R. E., Richardson, J. A., Schneider, M. D. & Yanagisawa, M., Nov 1 2003, In : Molecular and cellular biology. 23, 22, p. 8226-8232 7 p.

Research output: Contribution to journalArticle

63 Scopus citations
142 Scopus citations
29 Scopus citations

CDK5RAP2 regulates centriole engagement and cohesion in mice

Barrera, J. A., Kao, L. R., Hammer, R. E., Seemann, J., Fuchs, J. L. & Megraw, T. L., Mar 16 2010, In : Developmental cell. 18, 6, p. 913-926 14 p.

Research output: Contribution to journalArticle

97 Scopus citations

Cell-autonomous and nonautonomous actions of endothelin-A receptor signaling in craniofacial and cardiovascular development

Clouthier, D. E., Williams, S. C., Hammer, R. E., Richardson, J. A. & Yanagisawa, M., Sep 15 2003, In : Developmental Biology. 261, 2, p. 506-519 14 p.

Research output: Contribution to journalArticle

45 Scopus citations

Cell motility resulting from spontaneous polymerization waves

Doubrovinski, K. & Kruse, K., Dec 16 2011, In : Physical Review Letters. 107, 25, 258103.

Research output: Contribution to journalArticle

55 Scopus citations

Chapter 5 Recent Advances on in silico ADME Modeling

Wang, J. & Hou, T., 2009, In : Annual Reports in Computational Chemistry. 5, p. 101-127 27 p.

Research output: Contribution to journalArticle

26 Scopus citations

Characterization of a Dazl-GFP germ cell-specific reporter

Nicholas, C. R., Xu, E. Y., Banani, S. F., Hammer, R. E., Hamra, F. K. & Reijo Pera, R. A., Jul 1 2009, In : Genesis. 47, 2, p. 74-84 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Characterization of defective nucleotide excision repair in XPC mutant mice

Cheo, D. L., Ruven, H. J. T., Meira, L. B., Hammer, R. E., Burns, D. K., Tappe, N. J., Van Zeeland, A. A., Mullenders, L. H. F. & Friedberg, E. C., Mar 4 1997, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 374, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

99 Scopus citations

Characterization of flavonoids by aluminum complexation and collisionally activated dissociation

Zhang, J., Wang, J. & Brodbelt, J. S., Mar 1 2005, In : Journal of Mass Spectrometry. 40, 3, p. 350-363 14 p.

Research output: Contribution to journalArticle

41 Scopus citations

Characterization of psoriasiform and alopecic skin lesions in HLA-B27 transgenic rats

Yanagisawa, H., Richardson, J. A., Taurog, J. D. & Hammer, R. E., Jan 1 1995, In : American Journal of Pathology. 147, 4, p. 955-964 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Characterization of the knob domain of the adenovirus type 5 fiber protein expressed in Escherichia coli

Henry, L. J., Xia, D., Wilke, M. E., Deisenhofer, J. & Gerard, R. D., Aug 1994, In : Journal of virology. 68, 8, p. 5239-5246 8 p.

Research output: Contribution to journalArticle

Open Access
202 Scopus citations

Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation

Peterson, J. R., Bickford, L. C., Morgan, D., Kim, A. S., Ouerfelli, O., Kirschner, M. W. & Rosen, M. K., Aug 1 2004, In : Nature Structural and Molecular Biology. 11, 8, p. 747-755 9 p.

Research output: Contribution to journalArticle

138 Scopus citations

Cheminformatic Insight into the Differences between Terrestrial and Marine Originated Natural Products

Shang, J., Hu, B., Wang, J., Zhu, F., Kang, Y., Li, D., Sun, H., Kong, D. X. & Hou, T., Jun 25 2018, In : Journal of Chemical Information and Modeling. 58, 6, p. 1182-1193 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton

Janetopoulos, C., Ma, L., Devreotes, P. N. & Iglesias, P. A., Jun 15 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 24, p. 8951-8956 6 p.

Research output: Contribution to journalArticle

177 Scopus citations

Chimeric muscarinic cholinergic:β-adrenergic receptors that activate G(s) in response to muscarinic agonists

Wong, S. K. F., Parker, E. M. & Ross, E. M., May 16 1990, In : Journal of Biological Chemistry. 265, 11, p. 6219-6224 6 p.

Research output: Contribution to journalArticle

176 Scopus citations