Pharmacology - Ross Lab

Fingerprint Dive into the research topics where Pharmacology - Ross Lab is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

GTP-Binding Proteins Medicine & Life Sciences
GTPase-Activating Proteins Medicine & Life Sciences
Adenylyl Cyclases Medicine & Life Sciences
Guanosine Triphosphate Medicine & Life Sciences
Adrenergic Receptors Medicine & Life Sciences
Type C Phospholipases Medicine & Life Sciences
GTP Phosphohydrolases Medicine & Life Sciences
RGS Proteins Medicine & Life Sciences

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Research Output 1972 2018

2 Citations (Scopus)

Suppression of RGSz1 function optimizes the actions of opioid analgesics by mechanisms that involve the Wnt/β-catenin pathway

Gaspari, S., Purushothaman, I., Cogliani, V., Sakloth, F., Neve, R. L., Howland, D., Ring, R. H., Ross, E. M., Shen, L. & Zachariou, V., Feb 27 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 9, p. E2085-E2094

Research output: Contribution to journalArticle

GTP-Binding Protein Regulators
Catenins
Wnt Signaling Pathway
Opioid Analgesics
Morphine
1 Citation (Scopus)

The binding of activated Gq to phospholipase C- exhibits anomalous affinity

Navaratnarajah, P., Gershenson, A. & Ross, E. M., 2017, In : Journal of Biological Chemistry. 292, 40, p. 16787-16801 15 p.

Research output: Contribution to journalArticle

Type C Phospholipases
GTPase-Activating Proteins
Phosphatidylinositols
Protein Isoforms
Gq-G11 GTP-Binding Protein alpha Subunits
10 Citations (Scopus)

Amino acids regulate mTORC1 by an obligate two-step mechanism

Dyachok, J., Earnest, S., Iturraran, E. N., Cobb, M. H. & Ross, E. M., Oct 21 2016, In : Journal of Biological Chemistry. 291, 43, p. 22414-22426 13 p.

Research output: Contribution to journalArticle

Amino Acids
Chemical activation
Aminoacylation
mechanistic target of rapamycin complex 1
Tuberous Sclerosis