SY-Lab Tang Kang

Research Output

2020

AIFM2 blocks ferroptosis independent of ubiquinol metabolism

Dai, E., Zhang, W., Cong, D., Kang, R., Wang, J. & Tang, D., Mar 19 2020, In : Biochemical and Biophysical Research Communications. 523, 4, p. 966-971 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Alkaliptosis: a new weapon for cancer therapy

Liu, J., Kuang, F., Kang, R. & Tang, D., May 1 2020, In : Cancer Gene Therapy. 27, 5, p. 267-269 3 p.

Research output: Contribution to journalEditorial

Open Access
1 Scopus citations

Autophagy-Dependent Ferroptosis: Machinery and Regulation

Liu, J., Kuang, F., Kroemer, G., Klionsky, D. J., Kang, R. & Tang, D., Apr 16 2020, In : Cell Chemical Biology. 27, 4, p. 420-435 16 p.

Research output: Contribution to journalReview article

Open Access
3 Scopus citations

Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein

Dai, E., Han, L., Liu, J., Xie, Y., Kroemer, G., Klionsky, D. J., Zeh, H. J., Kang, R., Wang, J. & Tang, D., Jan 1 2020, (Accepted/In press) In : Autophagy.

Research output: Contribution to journalArticle

7 Scopus citations

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

Galluzzi, L., Vitale, I., Warren, S., Adjemian, S., Agostinis, P., Martinez, A. B., Chan, T. A., Coukos, G., Demaria, S., Deutsch, E., Draganov, D., Edelson, R. L., Formenti, S. C., Fucikova, J., Gabriele, L., Gaipl, U. S., Gameiro, S. R., Garg, A. D., Golden, E., Han, J. & 34 others, Harrington, K. J., Hemminki, A., Hodge, J. W., Hossain, D. M. S., Illidge, T., Karin, M., Kaufman, H. L., Kepp, O., Kroemer, G., Lasarte, J. J., Loi, S., Lotze, M. T., Manic, G., Merghoub, T., Melcher, A. A., Mossman, K. L., Prosper, F., Rekdal, Ø., Rescigno, M., Riganti, C., Sistigu, A., Smyth, M. J., Spisek, R., Stagg, J., Strauss, B. E., Tang, D., Tatsuno, K., Van Gool, S. W., Vandenabeele, P., Yamazaki, T., Zamarin, D., Zitvogel, L., Cesano, A. & Marincola, F. M., Mar 9 2020, In : Journal for ImmunoTherapy of Cancer. 8, 1, e000337.

Research output: Contribution to journalReview article

Open Access
6 Scopus citations

Correlation of Long Noncoding RNA SEMA6A-AS1 Expression with Clinical Outcome in HBV-Related Hepatocellular Carcinoma

Yu, S., Li, N., Wang, J., Fu, Y., Huang, Y., Yi, P., Chen, R., Tang, D., Hu, X. & Fan, X., Mar 2020, In : Clinical Therapeutics. 42, 3, p. 439-447 9 p.

Research output: Contribution to journalArticle

Open Access

ESCRT-III–dependent membrane repair blocks ferroptosis

Dai, E., Meng, L., Kang, R., Wang, X. & Tang, D., Feb 5 2020, In : Biochemical and Biophysical Research Communications. 522, 2, p. 415-421 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Interplay Between Lipid Metabolism and Autophagy

Xie, Y., Li, J., Kang, R. & Tang, D., Jun 3 2020, In : Frontiers in Cell and Developmental Biology. 8, 431.

Research output: Contribution to journalReview article

Open Access

Interplay between MTOR and GPX4 signaling modulates autophagy-dependent ferroptotic cancer cell death

Liu, Y., Wang, Y., Liu, J., Kang, R. & Tang, D., Jan 1 2020, (Accepted/In press) In : Cancer Gene Therapy.

Research output: Contribution to journalArticle

Long non-coding RNA SNHG5 regulates chemotherapy resistance through the miR-32/DNAJB9 axis in acute myeloid leukemia

Wang, D., Zeng, T., Lin, Z., Yan, L., Wang, F., Tang, L., Wang, L., Tang, D., Chen, P. & Yang, M., Mar 2020, In : Biomedicine and Pharmacotherapy. 123, 109802.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Mitochondrial DNA stress triggers autophagy-dependent ferroptotic death

Li, C., Zhang, Y., Liu, J., Kang, R., Klionsky, D. J. & Tang, D., Jan 1 2020, (Accepted/In press) In : Autophagy.

Research output: Contribution to journalArticle

2 Scopus citations

Strategic plan for management of COVID-19 in paediatric haematology and oncology departments

He, Y., Lin, Z., Tang, D., Yang, Y., Wang, T. & Yang, M., May 2020, In : The Lancet Haematology. 7, 5, p. e359-e362

Research output: Contribution to journalComment/debate

Open Access
3 Scopus citations

Targeting GRP78-dependent AR-V7 protein degradation overcomes castration-resistance in prostate cancer therapy

Liao, Y., Liu, Y., Xia, X., Shao, Z., Huang, C., He, J., Jiang, L., Tang, D., Liu, J. & Huang, H., Jan 1 2020, In : Theranostics. 10, 8, p. 3366-3381 16 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

The circadian clock protects against ferroptosis-induced sterile inflammation

Liu, Y., Wang, Y., Liu, J., Kang, R. & Tang, D., May 7 2020, In : Biochemical and Biophysical Research Communications. 525, 3, p. 620-625 6 p.

Research output: Contribution to journalArticle

The Multifaceted Effects of Autophagy on the Tumor Microenvironment

Kang, R., Zeh, H., Lotze, M. & Tang, D., Jan 1 2020, Advances in Experimental Medicine and Biology. Springer, p. 99-114 16 p. (Advances in Experimental Medicine and Biology; vol. 1225).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

TMEM173 Drives Lethal Coagulation in Sepsis

Zhang, H., Zeng, L., Xie, M., Liu, J., Zhou, B., Wu, R., Cao, L., Kroemer, G., Wang, H., Billiar, T. R., Zeh, H. J., Kang, R., Jiang, J., Yu, Y. & Tang, D., Apr 8 2020, In : Cell Host and Microbe. 27, 4, p. 556-570.e6

Research output: Contribution to journalArticle

3 Scopus citations

Transcription factors in ferroptotic cell death

Dai, C., Chen, X., Li, J., Comish, P., Kang, R. & Tang, D., Jan 1 2020, (Accepted/In press) In : Cancer Gene Therapy.

Research output: Contribution to journalReview article

4 Scopus citations
2019

AGER-mediated lipid peroxidation drives caspase-11 inflammasome activation in sepsis

Chen, R., Zhu, S., Zeng, L., Wang, Q., Sheng, Y., Zhou, B., Tang, D. & Kang, R., Jan 1 2019, In : Frontiers in immunology. 10, AUG, 1904.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Autophagic degradation of the circadian clock regulator promotes ferroptosis

Liu, J., Yang, M., Kang, R., Klionsky, D. J. & Tang, D., Nov 2 2019, In : Autophagy. 15, 11, p. 2033-2035 3 p.

Research output: Contribution to journalComment/debate

13 Scopus citations

CAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis

Chen, R., Zeng, L., Zhu, S., Liu, J., Zeh, H. J., Kroemer, G., Wang, H., Billiar, T. R., Jiang, J., Tang, D. & Kang, R., Jan 1 2019, In : Science Advances. 5, 5, aav5562.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Clockophagy is a novel selective autophagy process favoring ferroptosis

Yang, M., Chen, P., Liu, J., Zhu, S., Kroemer, G., Klionsky, D. J., Lotze, M. T., Zeh, H. J., Kang, R. & Tang, D., Jul 24 2019, In : Science Advances. 5, 7, eaaw2238.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

DNA released from neutrophil extracellular traps (NETs) activates pancreatic stellate cells and enhances pancreatic tumor growth

Miller-Ocuin, J. L., Liang, X., Boone, B. A., Doerfler, W. R., Singhi, A. D., Tang, D., Kang, R., Lotze, M. T. & Zeh, H. J., Sep 2 2019, In : OncoImmunology. 8, 9, e1605822.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Ferroptosis in health and disease

Tang, D., Oct 10 2019, Springer International Publishing. 303 p.

Research output: Book/ReportBook

Ferroptosis is a type of autophagy-dependent cell death

Zhou, B., Liu, J., Kang, R., Klionsky, D. J., Kroemer, G. & Tang, D., Jan 1 2019, (Accepted/In press) In : Seminars in Cancer Biology.

Research output: Contribution to journalReview article

41 Scopus citations

Heat shock proteins: Endogenous modulators of ferroptosis

Kang, R. & Tang, D., Oct 10 2019, Ferroptosis in Health and Disease. Springer International Publishing, p. 61-81 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Lipid storage and lipophagy regulates ferroptosis

Bai, Y., Meng, L., Han, L., Jia, Y., Zhao, Y., Gao, H., Kang, R., Wang, X., Tang, D. & Dai, E., Jan 22 2019, In : Biochemical and Biophysical Research Communications. 508, 4, p. 997-1003 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Mitochondrial quality control mediated by PINK1 and PRKN: links to iron metabolism and tumor immunity

Kang, R., Xie, Y., Zeh, H. J., Klionsky, D. J. & Tang, D., Jan 2 2019, In : Autophagy. 15, 1, p. 172-173 2 p.

Research output: Contribution to journalComment/debate

5 Scopus citations

Parkin facilitates proteasome inhibitor-induced apoptosis via suppression of NF-κB activity in hepatocellular carcinoma

Zhang, X., Lin, C., Song, J., Chen, H., Chen, X., Ren, L., Zhou, Z., Pan, J., Yang, Z., Bao, W., Ke, X., Yang, J., Liang, Y., Huang, H., Tang, D., Jiang, L. & Liu, J., Oct 1 2019, In : Cell Death and Disease. 10, 10, 719.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Regulation and function of autophagy during ferroptosis

Tang, D. & Kang, R., Oct 10 2019, Ferroptosis in Health and Disease. Springer International Publishing, p. 43-59 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

The HBx–CTTN interaction promotes cell proliferation and migration of hepatocellular carcinoma via CREB1

Li, Y., Fu, Y., Hu, X., Sun, L., Tang, D., Li, N., Peng, F. & Fan, X. G., Jun 1 2019, In : Cell Death and Disease. 10, 6, 405.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

The molecular machinery of regulated cell death

Tang, D., Kang, R., Berghe, T. V., Vandenabeele, P. & Kroemer, G., May 1 2019, In : Cell Research. 29, 5, p. 347-364 18 p.

Research output: Contribution to journalReview article

Open Access
93 Scopus citations

The release and activity of HMGB1 in ferroptosis

Wen, Q., Liu, J., Kang, R., Zhou, B. & Tang, D., Mar 5 2019, In : Biochemical and Biophysical Research Communications. 510, 2, p. 278-283 6 p.

Research output: Contribution to journalArticle

21 Scopus citations
2018

BECN1 is a new driver of ferroptosis

Kang, R., Zhu, S., Zeh, H. J., Klionsky, D. J. & Tang, D., Dec 2 2018, In : Autophagy. 14, 12, p. 2173-2175 3 p.

Research output: Contribution to journalComment/debate

19 Scopus citations

Response to comment on “ALK is a therapeutic target for lethal sepsis”

Tang, D. & Kang, R., Dec 12 2018, In : Science Translational Medicine. 10, 471, eaas9817.

Research output: Contribution to journalComment/debate

Open Access

The STING-STAT6 pathway drives Cas9-induced host response in human monocytes

Kang, R., Zhu, S., Zeh, H. & Tang, D., Nov 17 2018, In : Biochemical and Biophysical Research Communications. 506, 1, p. 278-283 6 p.

Research output: Contribution to journalArticle

2 Scopus citations
2012

Damage associated molecular pattern molecule-induced micrornas (DAMPmiRs) in human peripheral blood mononuclear cells

Unlu, S., Tang, S., Wang, E. N., Martinez, I., Tang, D., Bianchi, M. E., Zeh, H. J. & Lotze, M. T., Jun 22 2012, In : PloS one. 7, 6, e38899.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations
2011

Autophagy regulates myeloid cell differentiation by p62/SQSTM1-mediated degradation of PML-RARα oncoprotein

Wang, Z., Cao, L., Kang, R., Yang, M., Liu, L., Zhao, Y., Yu, Y., Xie, M., Yin, X., Livesey, K. M. & Tang, D., Apr 2011, In : Autophagy. 7, 4, p. 401-411 11 p.

Research output: Contribution to journalArticle

Open Access
96 Scopus citations