SY-Lab Tang Kang

Research Output 2018 2019

2019
1 Citation (Scopus)

AGER-mediated lipid peroxidation drives caspase-11 inflammasome activation in sepsis

Chen, R., Zhu, S., Zeng, L., Wang, Q., Sheng, Y., Zhou, B., Tang, D. & Kang, R., Jan 1 2019, In : Frontiers in immunology. 10, AUG, 1904.

Research output: Contribution to journalArticle

Open Access
Inflammasomes
Caspases
Lipid Peroxidation
Sepsis
Lipopolysaccharides

Alkaliptosis: a new weapon for cancer therapy

Liu, J., Kuang, F., Kang, R. & Tang, D., Jan 1 2019, (Accepted/In press) In : Cancer Gene Therapy.

Research output: Contribution to journalEditorial

Open Access
Weapons
Cell Death
Neoplasms
Therapeutics
Autophagy
5 Citations (Scopus)

Autophagic degradation of the circadian clock regulator promotes ferroptosis

Liu, J., Yang, M., Kang, R., Klionsky, D. J. & Tang, D., Nov 2 2019, In : Autophagy. 15, 11, p. 2033-2035 3 p.

Research output: Contribution to journalComment/debate

Circadian Clocks
Autophagy
Cell Death
Lipid Peroxidation
Sulfasalazine
2 Citations (Scopus)

CAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis

Chen, R., Zeng, L., Zhu, S., Liu, J., Zeh, H. J., Kroemer, G., Wang, H., Billiar, T. R., Jiang, J., Tang, D. & Kang, R., Jan 1 2019, In : Science Advances. 5, 5, aav5562.

Research output: Contribution to journalArticle

Open Access
metabolism
epinephrine
activation
macrophages
interleukins
8 Citations (Scopus)

Clockophagy is a novel selective autophagy process favoring ferroptosis

Yang, M., Chen, P., Liu, J., Zhu, S., Kroemer, G., Klionsky, D. J., Lotze, M. T., Zeh, H. J., Kang, R. & Tang, D., Jul 24 2019, In : Science Advances. 5, 7, eaaw2238.

Research output: Contribution to journalArticle

Open Access
death
degradation
tumors
cargo
cultured cells
1 Citation (Scopus)

DNA released from neutrophil extracellular traps (NETs) activates pancreatic stellate cells and enhances pancreatic tumor growth

Miller-Ocuin, J. L., Liang, X., Boone, B. A., Doerfler, W. R., Singhi, A. D., Tang, D., Kang, R., Lotze, M. T. & Zeh, H. J., Sep 2 2019, In : OncoImmunology. 8, 9, e1605822.

Research output: Contribution to journalArticle

Open Access
Pancreatic Stellate Cells
DNA
Growth
Pancreatic Neoplasms
Neoplasms
22 Citations (Scopus)

Ferroptosis is a type of autophagy-dependent cell death

Zhou, B., Liu, J., Kang, R., Klionsky, D. J., Kroemer, G. & Tang, D., Jan 1 2019, (Accepted/In press) In : Seminars in Cancer Biology.

Research output: Contribution to journalReview article

Autophagy
Cell Death
Recycling
Cell Survival
Necrosis
10 Citations (Scopus)

Lipid storage and lipophagy regulates ferroptosis

Bai, Y., Meng, L., Han, L., Jia, Y., Zhao, Y., Gao, H., Kang, R., Wang, X., Tang, D. & Dai, E., Jan 22 2019, In : Biochemical and Biophysical Research Communications. 508, 4, p. 997-1003 7 p.

Research output: Contribution to journalArticle

Cell Death
Lipids
Cell death
Lipid Peroxidation
Hepatocytes
4 Citations (Scopus)

Mitochondrial quality control mediated by PINK1 and PRKN: links to iron metabolism and tumor immunity

Kang, R., Xie, Y., Zeh, H. J., Klionsky, D. J. & Tang, D., Jan 2 2019, In : Autophagy. 15, 1, p. 172-173 2 p.

Research output: Contribution to journalComment/debate

Quality Control
Immunity
Iron
Inflammasomes
HMGB1 Protein

Parkin facilitates proteasome inhibitor-induced apoptosis via suppression of NF-κB activity in hepatocellular carcinoma

Zhang, X., Lin, C., Song, J., Chen, H., Chen, X., Ren, L., Zhou, Z., Pan, J., Yang, Z., Bao, W., Ke, X., Yang, J., Liang, Y., Huang, H., Tang, D., Jiang, L. & Liu, J., Oct 1 2019, In : Cell Death and Disease. 10, 10, 719.

Research output: Contribution to journalArticle

Open Access
Proteasome Inhibitors
NF-kappa B
Hepatocellular Carcinoma
Apoptosis
Proteolysis
1 Citation (Scopus)

The HBx–CTTN interaction promotes cell proliferation and migration of hepatocellular carcinoma via CREB1

Li, Y., Fu, Y., Hu, X., Sun, L., Tang, D., Li, N., Peng, F. & Fan, X. G., Jun 1 2019, In : Cell Death and Disease. 10, 6, 405.

Research output: Contribution to journalArticle

Open Access
Cortactin
Cell Movement
Hepatocellular Carcinoma
Cell Proliferation
Proteomics
42 Citations (Scopus)

The molecular machinery of regulated cell death

Tang, D., Kang, R., Berghe, T. V., Vandenabeele, P. & Kroemer, G., May 1 2019, In : Cell Research. 29, 5, p. 347-364 18 p.

Research output: Contribution to journalReview article

Open Access
Cell Death
Autophagy
Lysosomes
Pathology
9 Citations (Scopus)

The release and activity of HMGB1 in ferroptosis

Wen, Q., Liu, J., Kang, R., Zhou, B. & Tang, D., Mar 5 2019, In : Biochemical and Biophysical Research Communications. 510, 2, p. 278-283 6 p.

Research output: Contribution to journalArticle

HMGB1 Protein
Autophagy
Inflammation
Acetylation
Iron Overload
2018
11 Citations (Scopus)

BECN1 is a new driver of ferroptosis

Kang, R., Zhu, S., Zeh, H. J., Klionsky, D. J. & Tang, D., Dec 2 2018, In : Autophagy. 14, 12, p. 2173-2175 3 p.

Research output: Contribution to journalComment/debate

Autophagy
Class III Phosphatidylinositol 3-Kinases
Cell Death
Antiporters
AMP-Activated Protein Kinases

Response to comment on “ALK is a therapeutic target for lethal sepsis”

Tang, D. & Kang, R., Dec 12 2018, In : Science Translational Medicine. 10, 471, eaas9817.

Research output: Contribution to journalComment/debate

Open Access
Sepsis
Therapeutics
1 Citation (Scopus)

The STING-STAT6 pathway drives Cas9-induced host response in human monocytes

Kang, R., Zhu, S., Zeh, H. & Tang, D., Nov 17 2018, In : Biochemical and Biophysical Research Communications. 506, 1, p. 278-283 6 p.

Research output: Contribution to journalArticle

CRISPR-Associated Proteins
Monocytes
Clustered Regularly Interspaced Short Palindromic Repeats
Gene therapy
CD40 Ligand