• 9354 Citations
  • 52 h-Index
19992019
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Fingerprint Dive into the research topics where Agnieszka Witkiewicz is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles
Neoplasms Medicine & Life Sciences
Adenocarcinoma Medicine & Life Sciences
Pancreatic Neoplasms Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Caveolin 1 Medicine & Life Sciences
gemcitabine Medicine & Life Sciences
Retinoblastoma Medicine & Life Sciences
Carcinoma, Intraductal, Noninfiltrating Medicine & Life Sciences

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Research Output 1999 2019

1 Citation (Scopus)

Cell Cycle and Beyond: Exploiting New RB1 Controlled Mechanisms for Cancer Therapy

Knudsen, E. S., Pruitt, S. C., Hershberger, P. A., Witkiewicz, A. & Goodrich, D. W., Jan 1 2019, In : Trends in Cancer.

Research output: Contribution to journalReview article

Cell Cycle
Neoplasms
Therapeutics
Cyclin-Dependent Kinase 6
Cyclin-Dependent Kinase 4

Cell cycle plasticity driven by MTOR signaling: integral resistance to CDK4/6 inhibition in patient-derived models of pancreatic cancer

Knudsen, E. S., Kumarasamy, V., Ruiz, A., Sivinski, J., Chung, S., Grant, A., Vail, P., Chauhan, S. S., Jie, T., Riall, T. S. & Witkiewicz, A., Jan 1 2019, In : Oncogene.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Transcriptome
Cell Cycle
Adenocarcinoma
Cyclins
24 Citations (Scopus)

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

Bryant, K. L., Stalnecker, C. A., Zeitouni, D., Klomp, J. E., Peng, S., Tikunov, A. P., Gunda, V., Pierobon, M., Waters, A. M., George, S. D., Tomar, G., Papke, B., Hobbs, G. A., Yan, L., Hayes, T. K., Diehl, J. N., Goode, G. D., Chaika, N. V., Wang, Y., Zhang, G. F. & 11 others, Witkiewicz, A., Knudsen, E. S., Petricoin, E. F., Singh, P. K., Macdonald, J. M., Tran, N. L., Lyssiotis, C. A., Ying, H., Kimmelman, A. C., Cox, A. D. & Der, C. J., Apr 1 2019, In : Nature Medicine. 25, 4, p. 628-640 13 p.

Research output: Contribution to journalArticle

Autophagy
Chloroquine
Pancreatic Neoplasms
Fluxes
Adenocarcinoma

Coordinately targeting cell-cycle checkpoint functions in integrated models of pancreatic cancer

Chung, S., Vail, P., Witkiewicz, A. & Knudsen, E. S., Apr 1 2019, In : Clinical Cancer Research. 25, 7, p. 2290-2304 15 p.

Research output: Contribution to journalArticle

gemcitabine
Cell Cycle Checkpoints
Pancreatic Neoplasms
Adenocarcinoma
Preclinical Drug Evaluations

Interrogating Mutant Allele Expression via Customized Reference Genomes to Define Influential Cancer Mutations

Grant, A. D., Vail, P., Padi, M., Witkiewicz, A. & Knudsen, E. S., Dec 1 2019, In : Scientific Reports. 9, 1, 12766.

Research output: Contribution to journalArticle

Open Access
Alleles
Genome
Mutation
Neoplasms
vif Genes