• 10101 Citations
  • 55 h-Index
19992020

Research output per year

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Research Output

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Review article
2019

Cell Cycle and Beyond: Exploiting New RB1 Controlled Mechanisms for Cancer Therapy

Knudsen, E. S., Pruitt, S. C., Hershberger, P. A., Witkiewicz, A. & Goodrich, D. W., Jan 1 2019, In : Trends in Cancer.

Research output: Contribution to journalReview article

6 Scopus citations
2017

The Strange Case of CDK4/6 Inhibitors: Mechanisms, Resistance, and Combination Strategies

Knudsen, E. S. & Witkiewicz, A. K., Jan 1 2017, In : Trends in Cancer. 3, 1, p. 39-55 17 p.

Research output: Contribution to journalReview article

56 Scopus citations
2015

The history and future of targeting cyclin-dependent kinases in cancer therapy

Asghar, U., Witkiewicz, A. K., Turner, N. C. & Knudsen, E. S., Jan 1 2015, In : Nature Reviews Drug Discovery. 14, 2, p. 130-146 17 p.

Research output: Contribution to journalReview article

591 Scopus citations
2014

Retinoblastoma tumor suppressor pathway in breast cancer: Prognosis, precision medicine, and therapeutic interventions

Witkiewicz, A. K. & Knudsen, E. S., May 7 2014, In : Breast Cancer Research. 16, 2, 207.

Research output: Contribution to journalReview article

63 Scopus citations
2011

Acinar cell carcinoma with prominent intraductal growth pattern: Case report and review of the literature

Toll, A. D., Mitchell, D., Yeo, C. J., Hruban, R. H. & Witkiewicz, A. K., Dec 1 2011, In : International Journal of Surgical Pathology. 19, 6, p. 795-799 5 p.

Research output: Contribution to journalReview article

17 Scopus citations

The meaning of p16ink4a expression in tumors: Functional significance, clinical associations and future developments

Witkiewicz, A. K., Knudsen, K. E., Dicker, A. P. & Knudsen, E. S., Aug 1 2011, In : Cell Cycle. 10, 15, p. 2497-2503 7 p.

Research output: Contribution to journalReview article

135 Scopus citations

The Past, Present, and Future of Biomarkers: A Need for Molecular Beacons for the Clinical Management of Pancreatic Cancer

Brody, J. R., Witkiewicz, A. K. & Yeo, C. J., Sep 1 2011, In : Advances in surgery. 45, 1, p. 301-321 21 p.

Research output: Contribution to journalReview article

19 Scopus citations
2010

Identifying pancreatic cancer patients for targeted treatment: The challenges and limitations of the current selection process and vision for the future

Showalter, S. L., Charles, S., Belin, J., Cozzitorto, J., Einstein, P., Richards, N. G., Sauter, P. K., Kennedy, E. P., Witkiewicz, A., Brody, J. R. & Yeo, C. J., Mar 1 2010, In : Expert Opinion on Drug Delivery. 7, 3, p. 273-284 12 p.

Research output: Contribution to journalReview article

12 Scopus citations

The autophagic tumor stroma model of cancer or "battery-operated tumor growth": A simple solution to the autophagy paradox

Martinez-Outschoorn, U. E., Whitaker-Menezes, D., Pavlides, S., Chiavarina, B., Bonuccelli, G., Trimmer, C., Tsirigos, A., Migneco, G., Witkiewicz, A. K., Balliet, R., Mercier, I., Wang, C., Flomenberg, N., Howell, A., Lin, Z., Caro, J., Pestell, R. G., Sotgia, F. & Lisanti, M. P., Nov 1 2010, In : Cell Cycle. 9, 21, p. 4297-4306 10 p.

Research output: Contribution to journalReview article

128 Scopus citations

Understanding the "lethal" drivers of tumor-stroma co-evolution: Emerging role(s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor micro-environment

Lisanti, M. P., Martinez-Outschoorn, U. E., Chiavarina, B., Pavlides, S., Whitaker-Menezes, D., Tsirigos, A., Witkiewicz, A., Lin, Z., Balliet, R., Howell, A. & Sotgia, F., Sep 15 2010, In : Cancer Biology and Therapy. 10, 6, p. 537-542 6 p.

Research output: Contribution to journalReview article

130 Scopus citations
2009

Margin positive pancreaticoduodenectomy is superior to palliative bypass in locally advanced pancreatic ductal adenocarcinoma

Lavu, H., Mascaro, A. A., Grenda, D. R., Sauter, P. K., Leiby, B. E., Croker, S. P., Witkiewicz, A., Berger, A. C., Rosato, E. L., Kennedy, E. P. & Yeo, C. J., Sep 17 2009, In : Journal of Gastrointestinal Surgery. 13, 11, p. 1937-1947 11 p.

Research output: Contribution to journalReview article

30 Scopus citations

Towards a new "stromal-based" classification system for human breast cancer prognosis and therapy

Witkiewicz, A. K., Casimiro, M. C., Dasgupta, A., Mercier, I., Wang, C., Bonuccelli, G., Jasmin, J. F., Frank, P. G., Pestell, R. G., Kleer, C. G., Sotgia, F. & Lisanti, M. P., Jun 1 2009, In : Cell Cycle. 8, 11, p. 1654-1658 5 p.

Research output: Contribution to journalReview article

Open Access
48 Scopus citations