• 4882 Citations
  • 33 h-Index
19982019
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Fingerprint Dive into the research topics where Chuo Chen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 10 Similar Profiles
Pyrroles Chemical Compounds
Porcupines Medicine & Life Sciences
Alkaloids Chemical Compounds
Catenins Medicine & Life Sciences
Skeleton Medicine & Life Sciences
Cycloaddition Chemical Compounds
Wnt Proteins Medicine & Life Sciences
Cycloaddition Reaction Medicine & Life Sciences

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Research Output 1998 2019

  • 4882 Citations
  • 33 h-Index
  • 63 Article
  • 1 Chapter
  • 1 Review article

Stereoselective fatty acylation is essential for the release of lipidated WNT proteins from the acyltransferase Porcupine (PORCN)

Tuladhar, R., Yarravarapu, N., Ma, Y., Zhang, C., Herbert, J., Kim, J., Chen, C. & Lum, L., Jan 1 2019, In : Journal of Biological Chemistry. 294, 16, p. 6273-6282 10 p.

Research output: Contribution to journalArticle

Porcupines
Acylation
Animals
Acyltransferases
Proteins

Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation

Wang, S., Han, L., Han, J., Li, P., Ding, Q., Zhang, Q. J., Liu, Z. P., Chen, C. & Yu, Y., Dec 1 2019, In : Nature chemical biology. 15, 12, p. 1223-1231 9 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Adenosine Diphosphate
Muscle Cells
DNA Damage
Cell Death

A synthetic combinatorial approach to disabling deviant Hedgehog signaling

Fan, C. W., Yarravarapu, N., Shi, H., Kulak, O., Kim, J., Chen, C. & Lum, L., Dec 1 2018, In : Scientific Reports. 8, 1, 1133.

Research output: Contribution to journalArticle

Histone Deacetylases
Medulloblastoma
Critical Pathways
Basal Cell Carcinoma
DNA-Binding Proteins
1 Citation (Scopus)

Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9

Zhang, L. S., Kang, X., Lu, J., Zhang, Y., Wu, X., Wu, G., Zheng, J., Tuladhar, R., Shi, H., Wang, Q., Morlock, L., Yao, H., Huang, J-S., Maire, P., Kim, J., Williams, N. S., Xu, J., Chen, C., Zhang, C. & Lum, L., Jan 1 2018, (Accepted/In press) In : EBioMedicine.

Research output: Contribution to journalArticle

Catenins
Acute Myeloid Leukemia
Neoplasms
Proteins
Genetic Translocation
2 Citations (Scopus)

Natural Products as Inspiration for the Development of New Synthetic Methods

Ma, Z. & Chen, C., Jan 1 2018, In : Journal of the Chinese Chemical Society. 65, 1, p. 43-59 17 p.

Research output: Contribution to journalArticle

Biological Products
Biosynthesis
Organic Chemistry