Combined targeting of estrogen receptor alpha and XPO1 prevent AKT activation, remodel metabolic pathways and induce autophagy to overcome tamoxifen resistance

Eylem Kulkoyluoglu-Cotul, Brandi Patrice Smith, Kinga Wrobel, Yiru Chen Zhao, Karen Lee Ann Chen, Kadriye Hieronymi, Ozan Berk Imir, Kevin Duong, Caitlin O’Callaghan, Aditi Mehta, Sunati Sahoo, Barbara B Haley, Hua Chang, Yosef Landesman, Zeynep Madak-Erdogan

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Medicine & Life Sciences