Pharmacology - Mangelsdorf Lab

Fingerprint Dive into the research topics where Pharmacology - Mangelsdorf Lab is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

Cytoplasmic and Nuclear Receptors Medicine & Life Sciences
Bile Acids and Salts Medicine & Life Sciences
Retinoid X Receptors Medicine & Life Sciences
Ligands Medicine & Life Sciences
Cholesterol Medicine & Life Sciences
Peroxisome Proliferator-Activated Receptors Medicine & Life Sciences
Retinoic Acid Receptors Medicine & Life Sciences
Liver Medicine & Life Sciences

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Research Output 1983 2019

6 Citations (Scopus)

A Dozen Years of Discovery: Insights into the Physiology and Pharmacology of FGF21

Kliewer, S. A. & Mangelsdorf, D. J., Feb 5 2019, In : Cell Metabolism. 29, 2, p. 246-253 8 p.

Research output: Contribution to journalReview article

Pharmacology
fibroblast growth factor 21

The orphan nuclear receptor SHP regulates er stress response by inhibiting XBP1s degradation

Sun, S., Kelekar, S., Kliewer, S. A. & Mangelsdorf, D. J., Aug 1 2019, In : Genes and Development. 33, 15-16, p. 1083-1094 12 p.

Research output: Contribution to journalArticle

Open Access
Orphan Nuclear Receptors
Exocrine Pancreas
Endoplasmic Reticulum Stress
Ubiquitination
Proteolysis
13 Citations (Scopus)

Methylprednisolone acetate induces, and ?7-dafachronic acid suppresses, Strongyloides stercoralis hyperinfection in NSG mice

Patton, J. B., Bonne-Année, S., Deckman, J., Hess, J. A., Torigian, A., Nolan, T. J., Wang, Z., Kliewer, S. A., Durham, A. C., Lee, J. J., Eberhard, M. L., Mangelsdorf, D. J., Lok, J. B. & Abraham, D., Jan 2 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 1, p. 204-209 6 p.

Research output: Contribution to journalArticle

Strongyloides stercoralis
Larva
Glucocorticoids
methylprednisolone acetate
dafachronic acid