Pharmacology - Mangelsdorf Lab

Fingerprint Dive into the research topics where Pharmacology - Mangelsdorf Lab is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

Cytoplasmic and Nuclear Receptors Medicine & Life Sciences
Bile Acids and Salts Medicine & Life Sciences
Retinoid X Receptors Medicine & Life Sciences
Ligands Medicine & Life Sciences
Cholesterol Medicine & Life Sciences
Peroxisome Proliferator-Activated Receptors Medicine & Life Sciences
Retinoic Acid Receptors Medicine & Life Sciences
Liver Medicine & Life Sciences

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Research Output 1983 2019

11 Citations (Scopus)

A Dozen Years of Discovery: Insights into the Physiology and Pharmacology of FGF21

Kliewer, S. A. & Mangelsdorf, D. J., Feb 5 2019, In : Cell Metabolism. 29, 2, p. 246-253 8 p.

Research output: Contribution to journalReview article

Pharmacology
fibroblast growth factor 21

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling

Choi, J. H., Zhong, X., McAlpine, W., Liao, T. C., Zhang Ph.D., D-W., Fang, B., Russell, J., Ludwig, S., Nair-Gill, E., Zhang, Z., Wang, K. W., Misawa, T., Zhan, X., Choi, M., Wang, T., Li, X., Tang, M., Sun, Q., Yu, L., Murray, A. R. & 2 others, Moresco, E. Y. & Beutler, B., Jan 1 2019, In : Science. 364, 6440, eaau0812.

Research output: Contribution to journalArticle

Lymphopoiesis
Catenins
Wnt2 Protein
Ethylnitrosourea
Wnt Signaling Pathway

Syndromic immune disorder caused by a viable hypomorphic allele of spliceosome component Snrnp40

Zhang, D., Yue, T., Choi, J. H., Nair-Gill, E., Zhong, X., Wang, K. W., Zhan, X., Li, X., Choi, M., Tang, M., Quan, J., Hildebrand, S., Moresco, E. M. Y. & Beutler, B., Jan 1 2019, (Accepted/In press) In : Nature Immunology.

Research output: Contribution to journalArticle

Spliceosomes
Immune System Diseases
Alleles
Hematopoietic Stem Cells
U5 Small Nuclear Ribonucleoproteins