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Molecular Biology

Fingerprint Dive into the research topics where Zhijian Chen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 20 Similar Profiles
Ubiquitin Medicine & Life Sciences
Ubiquitination Medicine & Life Sciences
Antiviral Agents Medicine & Life Sciences
Innate Immunity Medicine & Life Sciences
Interferon Type I Medicine & Life Sciences
Polyubiquitin Medicine & Life Sciences
GMP synthase (glutamine-hydrolyzing) Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Research Output 1990 2019

17 Citations (Scopus)

Autophagy induction via STING trafficking is a primordial function of the cGAS pathway

Gui, X., Yang, H., Li, T., Tan, X., Shi, P., Li, M., Du, F. & Chen, Z., Mar 14 2019, In : Nature. 567, 7747, p. 262-266 5 p.

Research output: Contribution to journalLetter

Autophagy
Interferons
GMP synthase (glutamine-hydrolyzing)
Phosphotransferases
Sea Anemones
18 Citations (Scopus)

cGAS in action: Expanding roles in immunity and inflammation

Ablasser, A. & Chen, Z., Mar 8 2019, In : Science (New York, N.Y.). 363, 6431

Research output: Contribution to journalReview article

Immunity
Inflammation
DNA
Infection
Therapeutics
13 Citations (Scopus)

Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP

Shang, G., Zhang, C., Chen, Z., Bai, X. & Zhang, X., Mar 21 2019, In : Nature. 567, 7748, p. 389-393 5 p.

Research output: Contribution to journalLetter

Ligands
Chickens
Cryoelectron Microscopy
Interferon Type I
Endoplasmic Reticulum
10 Citations (Scopus)

Structural basis of STING binding with and phosphorylation by TBK1

Zhang, C., Shang, G., Gui, X., Zhang, X., Bai, X. & Chen, Z., Jan 1 2019, In : Nature.

Research output: Contribution to journalLetter

Interferons
Phosphotransferases
Phosphorylation
Genes
Interferon Type I
6 Citations (Scopus)

A GTPase-activating protein– binding protein (G3BP1)/antiviral protein relay conveys arteriosclerotic Wnt signals in aortic smooth muscle cells

Ramachandran, B., Stabley, J. N., Cheng, S. L., Behrmann, A. S., Gay, A., Li, L., Mead, M., Kozlitina, J., Lemoff, A., Mirzaei, H., Chen, Z. & Towler, D. A., Jan 1 2018, In : Journal of Biological Chemistry. 293, 21, p. 7942-7968 27 p.

Research output: Contribution to journalArticle

GTPase-Activating Proteins
Methylation
Vascular Smooth Muscle
Protein Binding
Smooth Muscle Myocytes