• 71926 Citations
  • 119 h-Index
1984 …2020

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1991

Phosphoramidon inhibits the intracellular conversion of big endothelin-1 to endothelin-1 in cultured endothelial cells

Sawamura, T., Kasuya, Y., Matsushita, Y., Suzuki, N., Shinmi, O., Kishi, N., Sugita, Y., Yanagisawa, M., Goto, K., Masaki, T. & Kimura, S., Jan 31 1991, In : Biochemical and Biophysical Research Communications. 174, 2, p. 779-784 6 p.

Research output: Contribution to journalArticle

77 Scopus citations

Plasma concentrations of endothelin-1 and endothelin-3 are altered differently in various pathophysiological conditions in humans

Miyauchi, T., Sugishita, Y., Yamaguchi, I., Ajisaka, R., Tomizawa, T., Onizuka, M., Matsuda, M., Kono, I., Yanagisawa, M., Goto, K., Suzuki, N., Matsumoto, H. & Masaki, T., Jan 1 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S394-S397

Research output: Contribution to journalArticle

30 Scopus citations

Polarized secretion of endothelin-1 and big ET-1 in MDCK cells is inhibited by cell Na+flux and disrupted by NH4Cl

Uchida, S., Horie, M., Yanagisawa, M., Matsushita, Y., Kurokawa, K. & Ogata, E., Jan 1 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S226-S228

Research output: Contribution to journalArticle

15 Scopus citations

Possible role of endothelin in the pathogenesis of cerebral vasospasm

Shigeno, T., Mima, T., Yanagisawa, M., Saito, A., Fujimori, A., Shiba, R., Goto, K., Kimura, S., Yamashita, K., Yamasaki, Y., Masaki, T. & Takakura, K., Jan 1 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S480-S483

Research output: Contribution to journalArticle

21 Scopus citations

Prevention of cerebral vasospasm by actinomycin D

Shigeno, T., Mima, T., Yanagisawa, M., Siato, A., Goto, K., Yamashita, K., Takenouchi, T., Matsuura, N., Yamasaki, Y., Yamada, K., Masaki, T. & Takakura, K., Jan 1 1991, In : Journal of neurosurgery. 74, 6, p. 940-943 4 p.

Research output: Contribution to journalArticle

36 Scopus citations

Role of endothelin in the development of dahl hypertension

Goligorsky, M. S., Iijima, K., Morgan, M., Yanagisawa, M., Masaki, T., Lin, L., Nasjletti, A., Kaskel, F., Frazer, M. & Badr, K. F., Jan 1 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S484-S491

Research output: Contribution to journalArticle

25 Scopus citations

TaqI polymorphism at the human preproendothelin-1 gene (EDN1)

Watanabe, M., Yanagisawa, M., Hamaguchi, H., Kanazawa, I. & Masaki, T., Sep 25 1991, In : Nucleic acids research. 19, 18, 1 p.

Research output: Contribution to journalArticle

3 Scopus citations

Topographical localisation of endothelin mRNA and peptide immunoreactivity in neurones of the human brain

Giaid, A., Gibson, S. J., Herrero, M. T., Gentleman, S., Legon, S., Yanagisawa, M., Masaki, T., Ibrahim, N. B. N., Roberts, G. W., Rossi, M. L. & Polak, J. M., Jan 1 1991, In : Histochemistry. 95, 3, p. 303-314 12 p.

Research output: Contribution to journalArticle

146 Scopus citations
1990

Affinity labelling of endothelin receptor and characterization of solubilized endothelin–endothelin‐receptor complex

Miyazaki, H., Kondoh, M., Watanabe, H., Masuda, Y., Murakami, K., Takahashi, M., Yanagisawa, M., Kimura, S., Goto, K. & Masaki, T., Jan 1990, In : European Journal of Biochemistry. 187, 1, p. 125-129 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Analysis of big endothelin-1 digestion by cathepsin D

Sawamura, T., Shinmi, O., Kishi, N., Sugita, Y., Yanagisawa, M., Goto, K., Masaki, T. & Kimura, S., Oct 30 1990, In : Biochemical and Biophysical Research Communications. 172, 2, p. 883-889 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Cardiovascular Effects of the Endothelins

Masaki, T. & Yanagisawa, M., Dec 1990, In : Cardiovascular Drug Reviews. 8, 4, p. 373-385 13 p.

Research output: Contribution to journalArticle

33 Scopus citations

Cerebral microvessel endothelium is producing endothelin

Yoshimoto, S., Ishizaki, Y., Kurihara, H., Sasaki, T., Yoshizumi, M., Yanagisawa, M., Yazaki, Y., Masaki, T., Takakura, K. & Murota, S. I., Feb 5 1990, In : Brain Research. 508, 2, p. 283-285 3 p.

Research output: Contribution to journalArticle

116 Scopus citations

Characterization of endothelin converting enzyme activities in soluble fraction of bovine cultured endothelial cells

Sawamura, T., Kimura, S., Shinmi, O., Sugita, Y., Kobayashi, M., Mitsui, Y., Yanagisawa, M., Goto, K. & Masaki, T., Jun 29 1990, In : Biochemical and Biophysical Research Communications. 169, 3, p. 1138-1144 7 p.

Research output: Contribution to journalArticle

64 Scopus citations

Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor

Sakurai, T., Yanagisawa, M., Takuwa, Y., Miyazaki, H., Kimura, S., Goto, K. & Masaki, T., Jan 1 1990, In : Nature. 348, 6303, p. 732-735 4 p.

Research output: Contribution to journalArticle

2289 Scopus citations

Detection of endothelin-1 in the human plasma and in the perfusate of rat mesenteric artery

Goto, K., Fujimori, A., Miyauchi, T., Ishikawa, T., Suzuki, N., Yanagisawa, M., Kimura, S. & Masaki, T., Jan 1 1990, In : European Journal of Pharmacology. 183, 5, p. 1816-1817 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

Detection of endothelin immunoreactivity and mRNA in pulmonary tumours

Giaid, A., Hamid, Q. A., Springall, D. R., Yanagisawa, M., Shinmi, O., Sawamura, T., Masaki, T., Kimura, S., Corrin, B. & Polak, J. M., Sep 1990, In : The Journal of Pathology. 162, 1, p. 15-22 8 p.

Research output: Contribution to journalArticle

64 Scopus citations

Distinct vascular and intestinal smooth muscle myosin heavy chain mRNAs are encoded by a single-copy gene in the chicken

Hamada, Y., Yanagisawa, M., Katsuragawa, Y., Coleman, J. R., Nagata, S., Matsuda, G. & Masaki, T., Jul 16 1990, In : Biochemical and Biophysical Research Communications. 170, 1, p. 53-58 6 p.

Research output: Contribution to journalArticle

57 Scopus citations

Effect of endothelin on cardiovascular system

Masaki, T., Yanagisawa, M., Kimura, S., Takuwa, Y. & Goto, K., Jan 1 1990, In : Japanese Heart Journal. 31, 4, p. 517-518 2 p.

Research output: Contribution to journalArticle

Endothelin: A novel peptide in the posterior pituitary system

Yoshizawa, T., Shinmi, O., Giaid, A., Yanagisawa, M., Gibson, S. J., Kimura, S., Uchiyama, Y., Polak, J. M., Masaki, T. & Kanazawa, I., Jan 1 1990, In : Science. 247, 4941, p. 462-464 3 p.

Research output: Contribution to journalArticle

291 Scopus citations

Endothelin-induced vasoconstriction of cerebral and peripheral arteries of dogs

Saito, A., Mima, T., Shigeno, T., Yanagisawa, M., Goto, K., Kimura, S. & Masaki, T., Jan 1 1990, In : European Journal of Pharmacology. 183, 5, p. 1803-1804 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Endothelin receptor is coupled to phospholipase C via a pertussis toxin-insensitive guanine nucleotide-binding regulatory protein in vascular smooth muscle cells

Takuwa, Y., Kasuya, Y., Takuwa, N., Kudo, M., Yanagisawa, M., Goto, K., Masaki, T. & Yamashita, K., Mar 1990, In : Journal of Clinical Investigation. 85, 3, p. 653-658 6 p.

Research output: Contribution to journalArticle

Open Access
158 Scopus citations

Increased maternal plasma concentration of endothelin-1 during labor pain or on delivery and the existence of a large amount of endothelin-1 in amniotic fluid

Usuki, S., Saitoh, T., Sawamura, T., Suzuki, N., Shigemitsu, S., Yanagisawa, M., Goto, K., Onda, H., Fujino, M. & Masaki, T., Jan 1 1990, In : Gynecological Endocrinology. 4, 2, p. 85-97 13 p.

Research output: Contribution to journalArticle

54 Scopus citations

Interleukin 1 increases the production of endothelin-1 by cultured endothelial cells

Yoshizumi, M., Kurihara, H., Morita, T., Yamashita, T., Oh-hashi, Y., Sugiyama, T., Takaku, F., Yanagisawa, M., Masaki, T. & Yazaki, Y., Jan 15 1990, In : Biochemical and Biophysical Research Communications. 166, 1, p. 324-329 6 p.

Research output: Contribution to journalArticle

245 Scopus citations

Involvement of endothelin in the regulation of human vascular tonus - Potent vasoconstrictor effect and existence in endothelial cells

Miyauchi, T., Tomobe, Y., Shiba, R., Ishikawa, T., Yanagisawa, M., Kimura, S., Sugishita, Y., Ito, I., Goto, K. & Masaki, T., Jan 1 1990, In : Circulation. 81, 6, p. 1874-1880 7 p.

Research output: Contribution to journalArticle

Open Access
119 Scopus citations

Isolation of anti-endothelin receptor monoclonal antibodies for use in receptor characterization

Kondoh, M., Miyazaki, H., Watanabe, H., Shibata, T., Yanagisawa, M., Masaki, T. & Murakami, K., Oct 30 1990, In : Biochemical and Biophysical Research Communications. 172, 2, p. 503-510 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Mechanisms of increased sensitivity to endothelin-1 in aorta from spontaneously hypertensive rats

Tomobe, Y., Ishikawa, T., Yanagisawa, M., Kimura, S., Masaki, T. & Goto, K., Jan 1 1990, In : European Journal of Pharmacology. 183, 5, 1 p.

Research output: Contribution to journalArticle

4 Scopus citations

Monoclonal antibodies to endothelin: Application for sandwich immunoassays

Hamaoki, M., Kato, H., Sugi, M., Fujimoto, M., Kurihara, H., Yosizumi, M., Yanagisawa, M., Kimura, S., Masaki, T. & Yazaki, Y., Jan 1 1990, In : Hybridoma. 9, 1, p. 63-69 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Production of endothelin-1 by rat cultured mesangial cells

Sakamoto, H., Sasaki, S., Hirata, Y., Imai, T., Ando, K., Ida, T., Sakurai, T., Yanagisawa, M., Masaki, T. & Marumo, F., Jun 15 1990, In : Biochemical and Biophysical Research Communications. 169, 2, p. 462-468 7 p.

Research output: Contribution to journalArticle

105 Scopus citations

Purification and characterization of putative endothelin converting enzyme in bovine adrenal medulla: Evidence for a cathepsin D-like enzyme

Sawamura, T., Kimura, S., Shinmi, O., Sugita, Y., Yanagisawa, M., Goto, K. & Masaki, T., May 16 1990, In : Biochemical and Biophysical Research Communications. 168, 3, p. 1230-1236 7 p.

Research output: Contribution to journalArticle

72 Scopus citations

Role of endothelin in mechanisms of local blood pressure control

Masaki, T., Yanagisawa, M., Goto, K. & Kimura, S., Dec 1 1990, In : Journal of hypertension. 8, SUPPL. 7, p. S107-S112

Research output: Contribution to journalArticle

32 Scopus citations

Study on the Endothelin Gene and its Expression

Masaki, T., Yanagisawa, M., Inoue, A., Kimura, S. & Goto, K., Jan 1 1990, In : JAPANESE CIRCULATION JOURNAL. 54, 9, p. 1221-1225 5 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

The human endothelin family: cDNA cloning, complete primary structure and differential tissue expression of the three precursors

Yanagtsawa, M., Inoue, A., Imai, T., Matsushita, Y. & Masaki, T., Jul 5 1990, In : European Journal of Pharmacology. 183, 5, p. 1628-1629 2 p.

Research output: Contribution to journalArticle

1989

Analysis of endothelin related peptides in culture supernatant of porcine aortic endothelial cells: Evidence for biosynthetic pathway of endothelin-1

Sawamura, T., Kimura, S., Shinmi, O., Sugita, Y., Yanagisawa, M. & Masaki, T., Aug 15 1989, In : Biochemical and Biophysical Research Communications. 162, 3, p. 1287-1294 8 p.

Research output: Contribution to journalArticle

84 Scopus citations

A novel vasoactive peptide endothelin stimulates mitogenesis through inositol lipid turnover in Swiss 3T3 fibroblasts

Takuwa, N., Takuwa, Y., Yanagisawa, M., Yamashita, K. & Masaki, T., Jan 1 1989, In : Journal of Biological Chemistry. 264, 14, p. 7856-7861 6 p.

Research output: Contribution to journalArticle

423 Scopus citations

Autoradiographic distribution in rat tissues of binding sites for endothelin: A neuropeptide?

Koseki, C., Imai, M., Hirata, Y., Yanagisawa, M. & Masaki, T., Jan 1 1989, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 256, 4, p. 25/4

Research output: Contribution to journalArticle

360 Scopus citations

Autoradiographic localization of [125I]-endothelin-1 binding sites in rat brain

Koseki, C., Imai, M., Hirata, Y., Yanagisawa, M. & Masaki, T., Aug 1989, In : Neuroscience Research. 6, 6, p. 581-585 5 p.

Research output: Contribution to journalArticle

41 Scopus citations

Binding sites for endothelin-1 in rat tissues: An autoradiographic study

Koseki, C., Imai, M., Hirata, Y., Yanagisawa, M. & Masaki, T., Jan 1 1989, In : Journal of Cardiovascular Pharmacology. 13, p. S153-S154

Research output: Contribution to journalArticle

51 Scopus citations

Characteristics of pressor response to endothelin in spontaneously hypertensive and Wistar-Kyoto rats

Miyauchi, T., Ishikawa, T., Tomobe, Y., Yanagisawa, M., Kimura, S., Sugishita, Y., Ito, I., Goto, K. & Masaki, T., Jan 1 1989, In : Hypertension. 14, 4, p. 427-434 8 p.

Research output: Contribution to journalArticle

Open Access
99 Scopus citations

Conversion of big endothelin-1 to 21-residue endothelin-1 is essential for expression of full vasoconstrictor activity: Structure-activity relationships of big endothelin-1

Kimura, S., Kasuya, Y., Sawamura, T., Shinmi, O., Sugita, Y., Yanagisawa, M., Goto, K. & Masaki, T., Jan 1 1989, In : Journal of Cardiovascular Pharmacology. 13, p. S5-S7

Research output: Contribution to journalArticle

180 Scopus citations

Elimination of intravenously injected endothelin-1 from the circulation of the rat

Shiba, R., Yanagisawa, M., Miyauchi, T., Ishii, Y., Kimura, S., Uchiyama, Y., Masaki, T. & Goto, K., Jan 1 1989, In : Journal of Cardiovascular Pharmacology. 13, p. S98-S101

Research output: Contribution to journalArticle

104 Scopus citations
355 Scopus citations

Endothelin, its diverse biological activities and mechanisms of action

Takuwa, Y., Yanagisawa, M., Takuwa, N. & Masaki, T., 1989, In : Progress in Growth Factor Research. 1, 4, p. 195-206 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Endothelin 1, an endothelium-derived peptide, is expressed in neurons of the human spinal cord and dorsal root ganglia

Giaid, A., Gibson, S. J., Ibrahim, N. B. N., Legon, S., Bloom, S. R., Yanagisawa, M., Masaki, T., Varndell, I. M. & Polak, J. M., Jan 1 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 19, p. 7634-7638 5 p.

Research output: Contribution to journalArticle

Open Access
330 Scopus citations

Endothelin-1 acts in cerebral arteries from the adventitial but not from the luminal side

Shigeno, T., Mima, T., Takakura, K., Yanagisawa, M., Saito, A., Goto, K. & Masaki, T., Jan 1 1989, In : Journal of Cardiovascular Pharmacology. 13, p. S174-S176

Research output: Contribution to journalArticle

53 Scopus citations

Endothelin-1 depolarizes a ventral root potential in the newborn rat spinal cord

Yoshizawa, T., Kimura, S., Kanazawa, I., Yanagisawa, M. & Masaki, T., Jan 1 1989, In : Journal of Cardiovascular Pharmacology. 13, p. S216-S217

Research output: Contribution to journalArticle

26 Scopus citations

Endothelin-1 induces vasoconstriction through two functionally distinct pathways in porcine coronary artery: Contribution of phosphoinositide turnover

Kasuya, Y., Takuwa, Y., Yanagisawa, M., Kimura, S., Goto, K. & Masaki, T., Jun 30 1989, In : Biochemical and Biophysical Research Communications. 161, 3, p. 1049-1055 7 p.

Research output: Contribution to journalArticle

96 Scopus citations

Endothelin-3 is a novel neuropeptide: Isolation and sequence determination of endothelin-1 and endothelin-3 in porcine brain

Shinmi, O., Kimura, S., Sawamura, T., Sugita, Y., Yoshizawa, T., Uchiyama, Y., Yanagisawa, M., Goto, K., Masaki, T. & Kanazawa, I., Oct 16 1989, In : Biochemical and Biophysical Research Communications. 164, 1, p. 587-593 7 p.

Research output: Contribution to journalArticle

133 Scopus citations

Endothelin activates the dihydropyridine-sensitive, voltage-dependent Ca2+ channel in vascular smooth muscle

Goto, K., Kasuya, Y., Matsuki, N., Takuwa, Y., Kurihara, H., Ishikawa, T., Kimura, S., Yanagisawa, M. & Masaki, T., Jan 1 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 10, p. 3915-3918 4 p.

Research output: Contribution to journalArticle

Open Access
316 Scopus citations

Endothelin acts in feline and canine cerebral arteries from the adventitial side

Mima, T., Yanagisawa, M., Shigeno, T., Saito, A., Goto, K., Takakura, K. & Masaki, T., Nov 1989, In : Stroke. 20, 11, p. 1553-1556 4 p.

Research output: Contribution to journalArticle

Open Access
107 Scopus citations

Endothelin localizes in the dorsal horn and acts on the spinal neurones: Possible involvement of dihydropyridine-sensitive calcium channels and substance P release

Yoshizawa, T., Kimura, S., Kanazawa, I., Uchiyama, Y., Yanagisawa, M. & Masaki, T., Jul 31 1989, In : Neuroscience Letters. 102, 2-3, p. 179-184 6 p.

Research output: Contribution to journalArticle

119 Scopus citations